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Literature DB >> 8887050

Pyloric antral inhibition of gastrin release.

Abstract

Inconsistencies and omissions in current explanations for the well known depressions of gastric acid secretion and blood gastrin levels following acidification by antral stimulants are discussed. Evidence is presented which favors a reciprocal sensitivity relationship between the fundic mucosa and the antral G cells, such that blood gastrin levels rise when the secreting fundic mucosa is compromised and acid secretion in response to exogenous gastrin is increased when G cells are depressed or reduced. The functional connections between the two phenomena are considered to be nervous.

Entities: Disease Gene

Mesh：

Substances：
Gastrins

Year: 1996 PMID： 8887050 DOI： 10.1007/bf02347632

Source DB: PubMed Journal: J Gastroenterol ISSN： 0944-1174 Impact factor: 7.527

30 in total

1. Evidence for antral inhibition of pentagastrin from experiments using mucosal cooling.

Authors: T Kondo; D F Magee
Journal: J Physiol Date: 1977-08 Impact factor: 5.182

2. Is there a fundic factor which regulates G cells in the antrum?

Authors: P J Fabri; M A Fabian; W R Gower; T H Knierim
Journal: J Surg Res Date: 1989-07 Impact factor: 2.192

3. Stimulation of gastrin release and gastric secretion: effect of bombesin and a nonapeptide in fistula dogs with and without fundic vagotomy.

Authors: B I Hirschowitz; R G Gibson
Journal: Digestion Date: 1978 Impact factor: 3.216

4. The secretion of pepsin.

Authors: T Kondo; D F Magee
Journal: J Physiol Date: 1977-08 Impact factor: 5.182

5. Proceedings: Experimental hypergastrinaemia and antral-gastrin-cell hyperplasia in dogs.

Authors: H M Jennewein; P C Ganguli; F Waldeck; R Siewert; J M Polak; A G Pearse
Journal: Gut Date: 1974-10 Impact factor: 23.059

6. Gastrin response to insulin after selective, highly selective, and truncal vagotomy.

Authors: F Stadil; J F Rehfeld
Journal: Gastroenterology Date: 1974-01 Impact factor: 22.682

7. Gastric fundopyloric relationships: a discussion prompted by "Vagal stimulation and inhibition of acid secretion and gastrin-release-which aspects are cholinergic".

Authors: D F Magee
Journal: Mt Sinai J Med Date: 1982 Jan-Feb

Pyloric antral inhibition of gastrin release.

1. Evidence for antral inhibition of pentagastrin from experiments using mucosal cooling.

2. Is there a fundic factor which regulates G cells in the antrum?

3. Stimulation of gastrin release and gastric secretion: effect of bombesin and a nonapeptide in fistula dogs with and without fundic vagotomy.

4. The secretion of pepsin.

5. Proceedings: Experimental hypergastrinaemia and antral-gastrin-cell hyperplasia in dogs.

6. Gastrin response to insulin after selective, highly selective, and truncal vagotomy.

7. Gastric fundopyloric relationships: a discussion prompted by "Vagal stimulation and inhibition of acid secretion and gastrin-release-which aspects are cholinergic".

Review 8. The effect of antacids on gastrin release.

9. Antral acidity and gastric secretion.

10. Inhibition of gastrin-stimulated canine acid secretion by sham-feeding.

1. Constitutive achlorhydria in mucolipidosis type IV.

2. Mucolipidosis IV consists of one complementation group.