Literature DB >> 8885170

Antibodies against Candida: potential therapeutics?

R Matthews1, J Burnie.   

Abstract

For many years, there has been controversy over the role of antibodies in immunity to Candida, but recently specific antibodies to mannoproteins and hsp90 have been shown to be protective against murine candidiasis. Combined with technical advances in antibody engineering, this raises the possibility of harnessing such antibodies into a new range of therapeutics.

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Year:  1996        PMID: 8885170     DOI: 10.1016/0966-842x(96)10056-1

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  8 in total

Review 1.  Heat shock proteins in immune reactions.

Authors:  E Weigl; P Kopecek; M Raska; S Hradilová
Journal:  Folia Microbiol (Praha)       Date:  1999       Impact factor: 2.099

2.  Biochemical characterization of Candida albicans epitopes that can elicit protective and nonprotective antibodies.

Authors:  Y Han; T Kanbe; R Cherniak; J E Cutler
Journal:  Infect Immun       Date:  1997-10       Impact factor: 3.441

3.  A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis.

Authors:  C Bromuro; R La Valle; S Sandini; F Urbani; C M Ausiello; L Morelli; C Fé d'Ostiani; L Romani; A Cassone
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

4.  Identification of continuous B-cell epitopes on the protein moiety of the 58-kiloDalton cell wall mannoprotein of Candida albicans belonging to a family of immunodominant fungal antigens.

Authors:  A Viudes; S Perea; J L Lopez-Ribot
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

5.  Development of the primer set for the detection of the hsp60 gene in Trichophyton mentagrophytes cDNA.

Authors:  P Kopecek; M Raska; E Weigl
Journal:  Folia Microbiol (Praha)       Date:  1999       Impact factor: 2.099

6.  Protection against candidiasis by an immunoglobulin G3 (IgG3) monoclonal antibody specific for the same mannotriose as an IgM protective antibody.

Authors:  Y Han; M H Riesselman; J E Cutler
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

Review 7.  Serologic response to cell wall mannoproteins and proteins of Candida albicans.

Authors:  J P Martínez; M L Gil; J L López-Ribot; W L Chaffin
Journal:  Clin Microbiol Rev       Date:  1998-01       Impact factor: 26.132

8.  Low levels of antigenic variability in fluconazole-susceptible and -resistant Candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis.

Authors:  J L Lopez-Ribot; R K McAtee; W R Kirkpatrick; R La Valle; T F Patterson
Journal:  Clin Diagn Lab Immunol       Date:  1999-09
  8 in total

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