Literature DB >> 8883658

Hydroxyapatite cement to repair skull base defects: radiologic appearance.

J L Weissman1, C H Snyderman, B E Hirsch.   

Abstract

PURPOSE: To describe the radiologic appearance of hydroxyapatite cement (HAC), which, when mixed with liquid, forms a paste that can be contoured to osseous defects and, over time, becomes "osseointegrated" (native bone grows into the pores of the HAC and forms a strong chemical bond with the substance).
METHODS: Between March 1992 and June 1993, 24 adults (16 men, eight women) underwent skull base surgery that included reconstruction or closure with HAC. Fourteen patients had HAC placed in the paranasal sinuses or facial bones, and 10 had HAC placed in the mastoid cavity.
RESULTS: HAC is homogeneously radiopaque on CT scans and plain radiographs. Large amounts (ablating a frontal sinus or mastoid air cells) are readily seen; small amounts are inconspicuous. On MR images, HAC is a signal void. Infected HAC in one patient was surrounded be enhancing soft tissue on MR images, separated from native bone by an irregular radiolucent cleft on CT scans.
CONCLUSIONS: HAC is a valuable addition to the surgical armamentarium for the repair of skull base defects. More experience will determine the time course for normal osseointegration, as well as the typical appearance of infection.

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Year:  1996        PMID: 8883658      PMCID: PMC8338722     

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  5 in total

1.  Anterior skull base surgery.

Authors:  Moni Abraham Kuriakose; Nirav P Trivedi; Vikram Kekatpure
Journal:  Indian J Surg Oncol       Date:  2010-11-21

2.  The fate of porous hydroxyapatite granules used in facial skeletal augmentation.

Authors:  Bryan C Mendelson; Steve R Jacobson; Alain M Lavoipierre; Richard J Huggins
Journal:  Aesthetic Plast Surg       Date:  2010-02-26       Impact factor: 2.326

Review 3.  Extraction of natural hydroxyapatite for biomedical applications-A review.

Authors:  Mohamed Saiful Firdaus Hussin; Hasan Zuhudi Abdullah; Maizlinda Izwana Idris; Mohd Arizam Abdul Wahap
Journal:  Heliyon       Date:  2022-08-22

4.  A Natural Bone Cement-A Laboratory Novelty Led to the Development of Revolutionary New Biomaterials.

Authors:  L C Chow; S Takagi
Journal:  J Res Natl Inst Stand Technol       Date:  2001-12-01

Review 5.  Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review.

Authors:  Mythili Prakasam; Janis Locs; Kristine Salma-Ancane; Dagnija Loca; Alain Largeteau; Liga Berzina-Cimdina
Journal:  J Funct Biomater       Date:  2015-12-21
  5 in total

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