Literature DB >> 8882510

Mediation of serotonin-induced hyperventilation via 5-HT3-receptor in European eel Anguilla anguilla.

J J Janvier1, M Peyraud-Waïtzenegger, P Soulier.   

Abstract

The effects of serotonin (5-hydroxytryptamine) on ventilation were investigated by continuous measurements of intrabuccal pressure in unrestrained eel. Intravenous administration of 5-hydroxytryptamine (30 micrograms.kg-1) caused a large increase in ventilatory frequency (+ 100%) and amplitude (+ 140%). The 5-hydroxytryptamine-induced hyperventilation was blocked by the 5-HT3-receptor antagonists metoclopramide (1.0 mg.kg-1) or MDL72222 (1.0 mg.kg-1), and was insensitive to the 5-HT1/2-receptor antagonist methysergide (3.0 mg.kg-1) and to the 5-HT4-receptor antagonist DAU 6285 CL (3.0 mg.kg-1). The hyperventilatory response to 5-hydroxytryptamine could be mimicked by the 5-HT3 receptor agonist 1-phenylbiguanide (300 micrograms.kg-1). These results strongly implicate the 5-HT3-receptor as the mediator of the 5-hydroxytryptamine-induced hyperventilation in eel.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8882510     DOI： 10.1007/bf00301132

Source DB:  PubMed          Journal:  J Comp Physiol B        ISSN： 0174-1578            Impact factor:   2.200


  26 in total

1.  PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT.

Authors:  J GLOWINSKI; J AXELROD; I J KOPIN; R J WURTMAN
Journal:  J Pharmacol Exp Ther       Date:  1964-10       Impact factor: 4.030

2.  Effects of serotonin and substance P on bulbar respiratory neurons in vivo.

Authors:  O Rampin; O Pierrefiche; M Denavit-Saubié
Journal:  Brain Res       Date:  1993-09-17       Impact factor: 3.252

3.  Comparative cardiorespiratory effects produced by taurine and glycine applied to the ventral surface of the medulla.

Authors:  P J Gatti; J D Souza; I J Namath; A M Da Silva; J R Holtman; R Gillis
Journal:  J Pharmacol Exp Ther       Date:  1985-12       Impact factor: 4.030

4.  Blood-brain barrier for serotonin in the eel (Anguilla anguilla L.).

Authors:  G Genot; R Morfin; C Peyraud
Journal:  Comp Biochem Physiol C       Date:  1981

5.  Effects of 5-hydroxytryptamine on the afterhyperpolarization, spike frequency regulation, and oscillatory membrane properties in lamprey spinal cord neurons.

Authors:  P Wallén; J T Buchanan; S Grillner; R H Hill; J Christenson; T Hökfelt
Journal:  J Neurophysiol       Date:  1989-04       Impact factor: 2.714

6.  Serotoninergic and non-serotoninergic responses of phrenic motoneurones to raphe stimulation in the cat.

Authors:  P M Lalley
Journal:  J Physiol       Date:  1986-11       Impact factor: 5.182

7.  Sensory receptors in the first gill arch of rainbow trout.

Authors:  M L Burleson; W K Milsom
Journal:  Respir Physiol       Date:  1993-07

8.  Respiratory rhythm generation in the in vitro brain stem-spinal cord preparation of the neonatal rat.

Authors:  T Suzue
Journal:  J Physiol       Date:  1984-09       Impact factor: 5.182

9.  Catecholaminergic depressant effects on bulbar respiratory mechanisms.

Authors:  J Champagnat; M Denavit-Saubié; J L Henry; V Leviel
Journal:  Brain Res       Date:  1979-01-05       Impact factor: 3.252

10.  Oxygen uptake and transport by the rainbow trout during exposure to carbon monoxide.

Authors:  G F Holeton
Journal:  J Exp Biol       Date:  1971-02       Impact factor: 3.312
View more
  2 in total

1.  5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems.

Authors:  Michelle E Bartman; Julia E R Wilkerson; Stephen M Johnson
Journal:  Respir Physiol Neurobiol       Date:  2010-04-23       Impact factor: 1.931

Review 2.  Neurochemical Signalling Associated With Gill Oxygen Sensing and Ventilation: A Receptor Focused Mini-Review.

Authors:  Maddison Reed; Michael G Jonz
Journal:  Front Physiol       Date:  2022-07-13       Impact factor: 4.755
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.