Literature DB >> 8882230

The admission of Asian patients to intensive therapy units and its implications for kidney donation: a preliminary report from Coventry, UK.

C Exley1, J Sim, N G Reid, L Booth, S Jackson, N West.   

Abstract

OBJECTIVE: To determine the relative admission rates of Asian and non-Asian patients to intensive therapy units (ITUs) in Coventry and to explore the implications of these rates for the transplantation of organs to Asian people.
DESIGN: Examination of 1991 census data and a retrospective review of ITU admissions books. Data were collected on ethnic background, presenting diagnosis, and clinical outcome for each admission.
SETTING: The three ITUs in Coventry. PATIENTS: All admissions to the ITUs from 1990-93 inclusive.
RESULTS: Asian patients were admitted to ITUs disproportionately to their numbers in the Coventry population. Members of the Asian community were less than half as likely to be admitted to an ITU (p < 0.001) and more likely to die while there (p = 0.007) than members of the non-Asian population in Coventry. The proportions of patients referred to the transplant unit and the rates of subsequent donation do not seem to differ significantly for Asian and non-Asian patients (p = 0.26 in both cases).
CONCLUSIONS: There are clear implications for the availability of cadaveric kidney transplantation to Asian patients, given that few kidneys from non-Asian donors are histocompatible with Asian recipients. Indeed, in Asians, promotion of living related donation may be more effective in countering the organ shortfall than efforts to increase consent to cadaveric transplantation. However, it may be valuable to investigate any patterns of morbidity or social or cultural factors that might explain the initial low admissions rates to ITUs for Asian patients.

Entities:  

Mesh:

Year:  1996        PMID: 8882230      PMCID: PMC1060317          DOI: 10.1136/jech.50.4.447

Source DB:  PubMed          Journal:  J Epidemiol Community Health        ISSN: 0143-005X            Impact factor:   3.710


  11 in total

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3.  End-stage renal failure in Indo-Asians.

Authors:  R M Higgins; M E Edmunds; D C Dukes
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4.  Non-heart beating donors as a source of kidneys.

Authors:  A J Wing; R W Chang
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5.  Organ donation from intensive care units in England.

Authors:  S M Gore; C J Hinds; A J Rutherford
Journal:  BMJ       Date:  1989-11-11

6.  Increased prevalence of dialysis-dependent renal failure in ethnic minorities in the west Midlands.

Authors:  T J Clark; N T Richards; D Adu; J Michael
Journal:  Nephrol Dial Transplant       Date:  1993       Impact factor: 5.992

7.  Prevalence of diabetes in a predominantly Asian community: preliminary findings of the Coventry diabetes study.

Authors:  D Simmons; D R Williams; M J Powell
Journal:  BMJ       Date:  1989-01-07

8.  Increased incidence of end-stage renal failure secondary to diabetes mellitus in Asian ethnic groups in the United Kingdom.

Authors:  A C Burden; P G McNally; J Feehally; J Walls
Journal:  Diabet Med       Date:  1992 Aug-Sep       Impact factor: 4.359

9.  Population need for renal replacement therapy in Thames regions: ethnic dimension.

Authors:  P J Roderick; I Jones; V S Raleigh; M McGeown; N Mallick
Journal:  BMJ       Date:  1994-10-29

10.  The Southall Diabetes Survey: prevalence of known diabetes in Asians and Europeans.

Authors:  H M Mather; H Keen
Journal:  Br Med J (Clin Res Ed)       Date:  1985-10-19
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  1 in total

1.  Attitudes to organ donation among South Asians in an English high street.

Authors:  W Ahmed; S Harris; E Brown
Journal:  J R Soc Med       Date:  1999-12       Impact factor: 5.344

  1 in total

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