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Literature DB >> 8879557

Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus.

Abstract

2-alpha-Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a Ki of 4.2 +/- 0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.

Entities: Chemical Gene Species

Mesh：

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Year: 1996 PMID： 8879557 PMCID： PMC7172942 DOI： 10.1016/0968-0896(96)00123-x

Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641

26 in total

Review 1. Diversity in the sialic acids.

Authors: A Varki
Journal: Glycobiology Date: 1992-02 Impact factor: 4.313

2. Monovalent sialosides that bind tightly to influenza A virus.

Authors: P L Toogood; P K Galliker; G D Glick; J R Knowles
Journal: J Med Chem Date: 1991-10 Impact factor: 7.446

3. The Tecumseh study of respiratory illness. VI. Frequency of and relationship between outbreaks of coronavirus infection.

Authors: A S Monto; S K Lim
Journal: J Infect Dis Date: 1974-03 Impact factor: 5.226

4. Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones.

Authors: D L Bodian; R B Yamasaki; R L Buswell; J F Stearns; J M White; I D Kuntz
Journal: Biochemistry Date: 1993-03-30 Impact factor: 3.162

5. Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution.

Authors: J N Varghese; W G Laver; P M Colman
Journal: Nature Date: 1983 May 5-11 Impact factor: 49.962

6. Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs.

Authors: S J Watowich; J J Skehel; D C Wiley
Journal: Structure Date: 1994-08-15 Impact factor: 5.006

7. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.

Authors: C L White; M N Janakiraman; W G Laver; C Philippon; A Vasella; G M Air; M Luo
Journal: J Mol Biol Date: 1995-02-03 Impact factor: 5.469

Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus.

Review 1. Diversity in the sialic acids.

2. Monovalent sialosides that bind tightly to influenza A virus.

3. The Tecumseh study of respiratory illness. VI. Frequency of and relationship between outbreaks of coronavirus infection.

4. Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones.

5. Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution.

6. Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs.

7. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.

8. An outbreak of type C influenza in a children's home.

9. Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses.

10. Benzoic acid inhibitors of influenza virus neuraminidase.

1. Synthesis and inhibitory activity of sialic acid derivatives targeted at viral sialate-O-acetylesterases.

2. Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus.