Literature DB >> 887938

Glucocorticoid in inflammatory proliferative skin disease reduces arachidonic and hydroxyeicosatetraenoic acids.

S Hammarström, M Hamberg, E A Duell, M A Stawiski, T F Anderson, J J Voorhees.   

Abstract

Psoriasis is a prototype of several common, glucocorticoid responsive, inflammatory proliferative skin diseases. Within 28 hours, glucocorticoid reduced the increased concentration of free arachidonic acid in diseased tissue. This reduction was observed prior to visible improvement of disease and may be an important molecular mechanism for the therapeutic efficacy of glucocorticoids in psoriasis and similar inflammatory diseases.

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Year:  1977        PMID： 887938     DOI： 10.1126/science.887938

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants.

Authors:  Jung Won Lee; Su Jin Cho; Eun Ae Park; Seung Joo Lee
Journal:  Pediatr Nephrol       Date:  2006-06-22       Impact factor: 3.714

2.  Topical administration of 1,25-dihydroxyvitamin D3 for psoriasis: report of five cases.

Authors:  S Morimoto; T Onishi; S Imanaka; H Yukawa; T Kozuka; Y Kitano; K Yoshikawa; Y Kumahara
Journal:  Calcif Tissue Int       Date:  1986-02       Impact factor: 4.333

3.  Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids.

Authors:  J L Humes; E E Opas; M Galavage; D Soderman; R J Bonney
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

4.  Is half strength of 0.05 % betamethasone valerate cream still effective in the treatment of phimosis in young children?

Authors:  Paiboon Sookpotarom; Chanchuree Asawutmangkul; Benjaporn Srinithiwat; Sucheera Leethochawalit; Paisarn Vejchapipat
Journal:  Pediatr Surg Int       Date:  2013-04       Impact factor: 1.827

5.  Topical steroid treatment reduces arachidonic acid and leukotriene B4 in lesional skin of psoriasis.

Authors:  E Wong; R M Barr; F M Cunningham; K Mistry; P M Woollard; A I Mallet; M W Greaves
Journal:  Br J Clin Pharmacol       Date:  1986-12       Impact factor: 4.335

6.  LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.

Authors:  Cornelia Pipper; Natalie Bordag; Bernadette Reiter; Kyriakos Economides; Peter Florian; Thomas Birngruber; Frank Sinner; Manfred Bodenlenz; Anita Eberl
Journal:  J Lipid Res       Date:  2019-01-29       Impact factor: 5.922

7.  The effect of systemic prednisolone on arachidonic acid, and prostaglandin E2 and F2 alpha levels in human cutaneous inflammation.

Authors:  A Kobza Black; M W Greaves; C N Hensby
Journal:  Br J Clin Pharmacol       Date:  1982-09       Impact factor: 4.335

8.  Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

Authors:  L B Klickstein; C Shapleigh; E J Goetzl
Journal:  J Clin Invest       Date:  1980-11       Impact factor: 14.808

9.  Neutrophil response to LIF: lack of glucocorticoid effect despite enhanced chemokinesis.

Authors:  D P Lurie; F DeLustro; E C LeRoy
Journal:  Inflammation       Date:  1983-03       Impact factor: 4.092

Review 10.  Topical glucocorticoids and the skin--mechanisms of action: an update.

Authors:  A Ahluwalia
Journal:  Mediators Inflamm       Date:  1998       Impact factor: 4.711
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