Literature DB >> 8878817

Second-generation antisense oligonucleotides: structure-activity relationships and the design of improved signal-transduction inhibitors.

K H Altmann1, D Fabbro, N M Dean, T Geiger, B P Monia, M Müller, P Nicklin.   

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Year:  1996        PMID： 8878817     DOI： 10.1042/bst0240630

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


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  16 in total

1.  Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.

Authors:  Bryan A Kraynack; Brenda F Baker
Journal:  RNA       Date:  2005-11-21       Impact factor: 4.942

2.  Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.

Authors:  I Berger; V Tereshko; H Ikeda; V E Marquez; M Egli
Journal:  Nucleic Acids Res       Date:  1998-05-15       Impact factor: 16.971

3.  Binding specificity and stability of duplexes formed by modified oligonucleotides with a 4096-hexanucleotide microarray.

Authors:  E Timofeev; A Mirzabekov
Journal:  Nucleic Acids Res       Date:  2001-06-15       Impact factor: 16.971

4.  Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits.

Authors:  Jifeng Zhang; Ying Yu; Kae Nakamura; Tomonari Koike; Ahmed Bilal Waqar; Xiaowei Zhang; Enqi Liu; Kazutoshi Nishijima; Shuji Kitajima; Masashi Shiomi; Zhongxia Qi; Jingwei Yu; Mark J Graham; Rosanne M Crooke; Tatsuro Ishida; Ken-Ichi Hirata; Eva Hurt-Camejo; Y Eugene Chen; Jianglin Fan
Journal:  J Atheroscler Thromb       Date:  2012-01-12       Impact factor: 4.928

5.  Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice.

Authors:  Toshiaki Shirai; Alexey S Revenko; Justin Tibbitts; Anh T P Ngo; Annachiara Mitrugno; Laura D Healy; Jennifer Johnson; Erik I Tucker; Monica T Hinds; Lisa M Coussens; Owen J T McCarty; Brett P Monia; András Gruber
Journal:  Blood Adv       Date:  2019-10-22

6.  Structural origins of the exonuclease resistance of a zwitterionic RNA.

Authors:  M Teplova; S T Wallace; V Tereshko; G Minasov; A M Symons; P D Cook; M Manoharan; M Egli
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

7.  Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells.

Authors:  R V Giles; D G Spiller; J Grzybowski; R E Clark; P Nicklin; D M Tidd
Journal:  Nucleic Acids Res       Date:  1998-04-01       Impact factor: 16.971

8.  2',5'-linked oligo-3'-deoxyribonucleoside phosphorothioate chimeras: thermal stability and antisense inhibition of gene expression.

Authors:  P Bhan; A Bhan; M Hong; J G Hartwell; J M Saunders; G D Hoke
Journal:  Nucleic Acids Res       Date:  1997-08-15       Impact factor: 16.971

9.  Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition?

Authors:  Marco Tonelli; Nikolai B Ulyanov; Todd M Billeci; Boleslaw Karwowski; Piotr Guga; Wojciech J Stec; Thomas L James
Journal:  Biophys J       Date:  2003-10       Impact factor: 4.033

10.  An improved synthesis of oligodeoxynucleotide N3'-->P5' phosphoramidates and their chimera using hindered phosphoramidite monomers and a novel handle for reverse phase purification.

Authors:  K L Fearon; B L Hirschbein; J S Nelson; M F Foy; M Q Nguyen; A Okruszek; S N McCurdy; J E Frediani; L A DeDionisio; A M Raible; E N Cagle; V Boyd
Journal:  Nucleic Acids Res       Date:  1998-08-15       Impact factor: 16.971
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