Literature DB >> 8878609

Use of Mono Mac 6 human monocytic cell line and J774 murine macrophage cell line in parallel antimycobacterial drug studies.

E L Wright1, D C Quenelle, W J Suling, W W Barrow.   

Abstract

The Mono Mac 6 (MM6) human monocytic cell line was evaluated with the established J774 murine macrophage cell line to ascertain its effectiveness in determining the intracellular activities of antimycobacterial drugs. Cells were infected with Mycobacterium tuberculosis H37Ra and treated with drug concentrations corresponding to the MICs, as well as to threefold higher than and threefold less than the MICs. Changes in CFU were compared after 7 days to determine significant differences between treated and nontreated groups. The results suggest that MM6 will make a useful model for testing the intracellular activities of antituberculosis drugs.

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Year:  1996        PMID： 8878609      PMCID： PMC163501     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Killing by antimycobacterial agents of AIDS-derived strains of Mycobacterium avium complex inside cells of the mouse macrophage cell line J774.

Authors:  D M Yajko; P S Nassos; C A Sanders; W K Hadley
Journal:  Am Rev Respir Dis       Date:  1989-11

2.  Antimycobacterial spectrum of sparfloxacin and its activities alone and in association with other drugs against Mycobacterium avium complex growing extracellularly and intracellularly in murine and human macrophages.

Authors:  N Rastogi; V Labrousse; K S Goh; J P De Sousa
Journal:  Antimicrob Agents Chemother       Date:  1991-12       Impact factor: 5.191

3.  Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

Authors:  J Carmichael; W G DeGraff; A F Gazdar; J D Minna; J B Mitchell
Journal:  Cancer Res       Date:  1987-02-15       Impact factor: 12.701

4.  Comparison of activities of rifapentine and rifampin against Mycobacterium tuberculosis residing in human macrophages.

Authors:  N Mor; B Simon; N Mezo; L Heifets
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

5.  Phagocytosis of Mycobacterium tuberculosis or particulate stimuli by human monocytic cells induces equivalent monocyte chemotactic protein-1 gene expression.

Authors:  J S Friedland; R J Shattock; G E Griffin
Journal:  Cytokine       Date:  1993-03       Impact factor: 3.861

6.  Macrophage uptake and retention of radiolabeled glycopeptidolipid antigens associated with the superficial L1 layer of Mycobacterium intracellulare serovar 20.

Authors:  L C Hooper; M M Johnson; V R Khera; W W Barrow
Journal:  Infect Immun       Date:  1986-10       Impact factor: 3.441

7.  Immunomodulation of human peripheral blood mononuclear cell functions by defined lipid fractions of Mycobacterium avium.

Authors:  W W Barrow; J P de Sousa; T L Davis; E L Wright; M Bachelet; N Rastogi
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

8.  Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes.

Authors:  H W Ziegler-Heitbrock; E Thiel; A Fütterer; V Herzog; A Wirtz; G Riethmüller
Journal:  Int J Cancer       Date:  1988-03-15       Impact factor: 7.396

9.  Phagocytosis of Mycobacterium tuberculosis modulates human immunodeficiency virus replication in human monocytic cells.

Authors:  R J Shattock; J S Friedland; G E Griffin
Journal:  J Gen Virol       Date:  1994-04       Impact factor: 3.891

10.  Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells.

Authors:  F Herrmann; S A Cannistra; H Levine; J D Griffin
Journal:  J Exp Med       Date:  1985-09-01       Impact factor: 14.307
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  11 in total

1.  Treatment of tuberculosis using a combination of sustained-release rifampin-loaded microspheres and oral dosing with isoniazid.

Authors:  D C Quenelle; G A Winchester; J K Staas; E L Barrow; W W Barrow
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

2.  Efficacy of microencapsulated rifampin in Mycobacterium tuberculosis-infected mice.

Authors:  D C Quenelle; J K Staas; G A Winchester; E L Barrow; W W Barrow
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

3.  Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium.

Authors:  L Collins; S G Franzblau
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

4.  Macrophages from patients with cirrhotic ascites showed function alteration of host defense receptor.

Authors:  Abdel Motaal M Ahmed; Abdel Gadir Y Kadaru; Ibtihal Omer; Ahmed M Musa; Khalid Enan; Isam M El Khidir; Roger Williams
Journal:  J Clin Exp Hepatol       Date:  2014-09-16

5.  Use of microsphere technology for targeted delivery of rifampin to Mycobacterium tuberculosis-infected macrophages.

Authors:  E L Barrow; G A Winchester; J K Staas; D C Quenelle; W W Barrow
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191

6.  Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase.

Authors:  W J Suling; L E Seitz; V Pathak; L Westbrook; E W Barrow; S Zywno-Van-Ginkel; R C Reynolds; J R Piper; W W Barrow
Journal:  Antimicrob Agents Chemother       Date:  2000-10       Impact factor: 5.191

7.  Rapid measurement of antituberculosis drug activity in vitro and in macrophages using bioluminescence.

Authors:  Nuria Andreu; Taryn Fletcher; Nitya Krishnan; Siouxsie Wiles; Brian D Robertson
Journal:  J Antimicrob Chemother       Date:  2011-11-17       Impact factor: 5.790

8.  Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).

Authors:  Cheryl de Vallière; Jesus Cosin-Roger; Simona Simmen; Kirstin Atrott; Hassan Melhem; Jonas Zeitz; Mehdi Madanchi; Irina Tcymbarevich; Michael Fried; Gerd A Kullak-Ublick; Stephan R Vavricka; Benjamin Misselwitz; Klaus Seuwen; Carsten A Wagner; Jyrki J Eloranta; Gerhard Rogler; Pedro A Ruiz
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2016-06-25

9.  A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells.

Authors:  Jeongmin Song; Matthew J Duncan; Guojie Li; Cheryl Chan; Richard Grady; Ann Stapleton; Soman N Abraham
Journal:  PLoS Pathog       Date:  2007-04       Impact factor: 6.823

10.  Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound.

Authors:  Naser F Al-Tannak; Oludotun A Phillips
Journal:  Sci Pharm       Date:  2017-10-02
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