| Literature DB >> 8877383 |
Y Sumi1, M T Itoh, T Muraki, T Suzuki.
Abstract
In order to develop a stain with increased sensitivity and selectivity for cadmium (Cd), we synthesized and characterized 2-(8-quinolylazo)-4,5-diphenylimidazole (QAI). This chelating agent was more than twice as sensitive for Cd than the best conventional staining agents, including benzothiazolylazo-beta-naphthol. Differentiation between Cd and zinc (Zn) was achieved by immersing tissue sections in TRIS(2-aminoethyl)amine before they were stained with QAI. This pretreatment made it possible to selectively stain for Cd by blocking Zn.Entities:
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Year: 1996 PMID: 8877383 DOI: 10.1007/bf02484404
Source DB: PubMed Journal: Histochem Cell Biol ISSN: 0948-6143 Impact factor: 4.304