Literature DB >> 8877145

Effect of Clostridium difficile toxin A on CD11/CD18 expression in vitro.

M Warny1, B Chatelain, M Delmée.   

Abstract

Clostridium difficile toxin A is chemotactic for neutrophils and induces their emigration into the colonic mucosae of rodents. We found that toxin A did not upregulate neutrophil beta 2 integrins on isolated human neutrophils. These data support the hypothesis that in C. difficile colitis, these adhesion molecules are upregulated by endogenous mediators.

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Year:  1996        PMID： 8877145      PMCID： PMC170416          DOI： 10.1128/cdli.3.5.605-607.1996

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  16 in total

Review 1.  Adhesion receptors of the immune system.

Authors:  T A Springer
Journal:  Nature       Date:  1990-08-02       Impact factor: 49.962

2.  Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors.

Authors:  T K Kishimoto; M A Jutila; E L Berg; E C Butcher
Journal:  Science       Date:  1989-09-15       Impact factor: 47.728

3.  Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface.

Authors:  L J Miller; D F Bainton; N Borregaard; T A Springer
Journal:  J Clin Invest       Date:  1987-08       Impact factor: 14.808

Review 4.  Clostridium difficile: its disease and toxins.

Authors:  D M Lyerly; H C Krivan; T D Wilkins
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

5.  Selective up-regulation of human granulocyte integrins and complement receptor 1 by cytokines.

Authors:  G A Limb; A S Hamblin; R A Wolstencroft; D C Dumonde
Journal:  Immunology       Date:  1991-12       Impact factor: 7.397

6.  Mechanisms underlying acute mast cell-induced leukocyte rolling and adhesion in vivo.

Authors:  J P Gaboury; B Johnston; X F Niu; P Kubes
Journal:  J Immunol       Date:  1995-01-15       Impact factor: 5.422

7.  Purification and characterization of toxins A and B of Clostridium difficile.

Authors:  N M Sullivan; S Pellett; T D Wilkins
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

8.  Differential effects of Clostridium difficile toxins A and B on rabbit ileum.

Authors:  G Triadafilopoulos; C Pothoulakis; M J O'Brien; J T LaMont
Journal:  Gastroenterology       Date:  1987-08       Impact factor: 22.682

9.  Cytokine response by human monocytes to Clostridium difficile toxin A and toxin B.

Authors:  W A Flegel; F Müller; W Däubener; H G Fischer; U Hadding; H Northoff
Journal:  Infect Immun       Date:  1991-10       Impact factor: 3.441

10.  Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes.

Authors:  C Pothoulakis; R Sullivan; D A Melnick; G Triadafilopoulos; A S Gadenne; T Meshulam; J T LaMont
Journal:  J Clin Invest       Date:  1988-06       Impact factor: 14.808
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