Late development of granuloma after liquid silicone injections.

In a 10-year experience with silicone injections involving 92 patients, there was subsequent development of a granuloma in 13 injection sites. Most of these occurred within 12 months, but some took a few years and one appeared 7 years later. It is believed that the injected material was medical grade liquid silicone, without additives or contaminants.