Literature DB >> 8869923

Malaria and macrophage function in Africans: a possible link with autoimmune disease?

G A Butcher1.   

Abstract

Systemic lupus erythematosus and sarcoidosis, both diseases in which immune responses are aberrant, are not found in Africans in West Africa, but their prevalence in people of West African descent in the USA and UK is higher than that for white people. It is argued here that malaria both prevents these diseases in West Africa by its effects on macrophage function, and has also selected for a predisposition to them.

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Year:  1996        PMID: 8869923     DOI: 10.1016/s0306-9877(96)90446-6

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  3 in total

Review 1.  Regulation of autoimmune inflammation by pro-inflammatory cytokines.

Authors:  Eugene Y Kim; Kamal D Moudgil
Journal:  Immunol Lett       Date:  2008-08-09       Impact factor: 3.685

2.  Exacerbation of autoimmune neuro-inflammation in mice cured from blood-stage Plasmodium berghei infection.

Authors:  Rodolfo Thomé; André Luis Bombeiro; Luidy Kazuo Issayama; Catarina Rapôso; Stefanie Costa Pinto Lopes; Thiago Alves da Costa; Rosária Di Gangi; Isadora Tassinari Ferreira; Ana Leda Figueiredo Longhini; Alexandre Leite Rodrigues Oliveira; Maria Alice da Cruz Höfling; Fábio Trindade Maranhão Costa; Liana Verinaud
Journal:  PLoS One       Date:  2014-10-17       Impact factor: 3.240

3.  Rate of red blood cell destruction varies in different strains of mice infected with Plasmodium berghei-ANKA after chronic exposure.

Authors:  Gideon Kofi Helegbe; Nguyen T Huy; Tetsuo Yanagi; Mohammed N Shuaibu; Akiko Yamazaki; Mihoko Kikuchi; Michio Yasunami; Kenji Hirayama
Journal:  Malar J       Date:  2009-05-05       Impact factor: 2.979

  3 in total

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