Literature DB >> 8866723

The determination of the extracellular concentration of brain glutamate using quantitative microdialysis.

M Miele1, M Berners, M G Boutelle, H Kusakabe, M Fillenz.   

Abstract

Quantitative microdialysis with two enzyme-based assays was used to determine the extracellular concentration of glutamate in the striatum of freely moving rats. From the difference between infused and dialysate glutamate a value of 3.0 +/- 0.6 microM for the extracellular glutamate concentration was computed by regression analysis. The in vivo recovery, derived from the slope of the regression line, was 50%.

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Year:  1996        PMID: 8866723     DOI: 10.1016/0006-8993(95)01371-7

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  13 in total

1.  Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate.

Authors:  M Demestre; M Boutelle; M Fillenz
Journal:  J Physiol       Date:  1997-03-15       Impact factor: 5.182

Review 2.  Regulation of synaptic transmission by ambient extracellular glutamate.

Authors:  David E Featherstone; Scott A Shippy
Journal:  Neuroscientist       Date:  2007-10-18       Impact factor: 7.519

3.  P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway.

Authors:  Holly C Hunsberger; Carolyn C Rudy; Seth R Batten; Greg A Gerhardt; Miranda N Reed
Journal:  J Neurochem       Date:  2014-10-31       Impact factor: 5.372

4.  Glutamate Transporters and Mitochondria: Signaling, Co-compartmentalization, Functional Coupling, and Future Directions.

Authors:  Michael B Robinson; Meredith L Lee; Sabrina DaSilva
Journal:  Neurochem Res       Date:  2020-01-30       Impact factor: 3.996

5.  Release of endogenous amino acids from the striatum from developing and adult mice in ischemia.

Authors:  Simo S Oja; Pirjo Saransaari
Journal:  Neurochem Res       Date:  2011-04-13       Impact factor: 3.996

6.  Facile fabrication of flexible glutamate biosensor using direct writing of platinum nanoparticle-based nanocomposite ink.

Authors:  Tran N H Nguyen; James K Nolan; Hyunsu Park; Stephanie Lam; Mara Fattah; Jessica C Page; Hang-Eun Joe; Martin B G Jun; Hyungwoo Lee; Sang Joon Kim; Riyi Shi; Hyowon Lee
Journal:  Biosens Bioelectron       Date:  2019-01-31       Impact factor: 10.618

7.  The source of physiologically stimulated glutamate efflux from the striatum of conscious rats.

Authors:  M Miele; M G Boutelle; M Fillenz
Journal:  J Physiol       Date:  1996-12-15       Impact factor: 5.182

8.  Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse.

Authors:  B R Miller; J L Dorner; M Shou; Y Sari; S J Barton; D R Sengelaub; R T Kennedy; G V Rebec
Journal:  Neuroscience       Date:  2008-02-15       Impact factor: 3.590

9.  Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.

Authors:  Simo S Oja; Pirjo Saransaari
Journal:  Neurochem Res       Date:  2009-04-03       Impact factor: 3.996

Review 10.  Recent trends in microdialysis sampling integrated with conventional and microanalytical systems for monitoring biological events: a review.

Authors:  Pradyot Nandi; Susan M Lunte
Journal:  Anal Chim Acta       Date:  2009-08-03       Impact factor: 6.558

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