Literature DB >> 8866293

Advanced maternal age: perinatal outcome when controlling for physician selection.

D C Lagrew1, M A Morgan, K Nakamoto, N Lagrew.   

Abstract

OBJECTIVE: Our purpose was to determine whether differences in maternal outcome because of maternal age could be controlled by the elimination of bias in physician selection. STUDY
DESIGN: We performed a case-control study that compared pregnancy outcomes of 164 patients delivered at our institution at > or = 40 years old with outcomes in a control group consisting of the next two deliveries by the same attending physician of women with ages 20 to 29 years. Retrospective analysis of the antepartum and intrapartum records was done to compare clinical outcome.
RESULTS: We observed a significant increased incidence of nulliparous cesarean delivery (p = 0.046), elevated results of glucose screens with a 50 gm load (p = 0.00002), and hypertension throughout pregnancy in the older patients in spite of controlling for physician selection. The older patient group was more likely to have used assisted reproductive techniques (p = 0.000005) and had higher baseline weights (p = 0.001) and maximum pregnancy weights (p = 0.042). However, the neonatal outcome was similar in both groups. Despite controlling for physician selection, we demonstrated increased rates of abdominal delivery, glucose intolerance, and hypertension in older patients. Fetal and neonatal outcomes were similar in both groups.
CONCLUSION: Women > or = 40 years old tend to have an increased incidence of a few pregnancy-related complications, even when controlling for physician selection.

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Year:  1996        PMID: 8866293

Source DB:  PubMed          Journal:  J Perinatol        ISSN: 0743-8346            Impact factor:   2.521


  2 in total

Review 1.  Significant effects of mild endogenous hormonal changes in humans: considerations for low-dose testing.

Authors:  F Brucker-Davis; K Thayer; T Colborn
Journal:  Environ Health Perspect       Date:  2001-03       Impact factor: 9.031

2.  The effects of weathering demonstrated by maternal age on low birth weight outcome in babies.

Authors:  Baba Usman Ahmadu; Bello Mustapha; Jonathan Isah Bappariya; Numfor Alfred; Zwabragi Joel
Journal:  Ethiop J Health Sci       Date:  2013-03
  2 in total

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