| Literature DB >> 8865807 |
C E Burnham1, B Buerk, C Schmidt, J C Bucuvalas.
Abstract
We report the cloning of a 2.2 kb cDNA encoding a Na(+)-and Cl- dependent betaine/GABA (gamma-aminobutyric acid) transporter from rat liver poly(A+) RNA. 5'-RACE revealed an additional 355 bases 5' to the 2.2 kb cDNA sequence. Northern analysis demonstrated two (2.2 kb and 2.6 kb) mRNA isoforms in rat liver. Betaine transporter mRNA was also detected in the brain, spleen, lung, and kidney using the 2.2 kb cDNA clone as a probe. Only the 2.6 kb mRNA from the liver hybridized with the 5'-RACE product.Entities:
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Year: 1996 PMID： 8865807 DOI： 10.1016/0005-2736(96)00118-6
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002