Literature DB >> 8865002

Unusual early recurrence of a cerebellar pilocytic astrocytoma following complete surgical resection. Case report and review of the literature.

P J Sioutos1, A J Hamilton, P K Narotam, M E Weinand.   

Abstract

Pilocytic cerebellar astrocytomas are usually benign tumors with generally an excellent prognosis following complete surgical resection. The goal of surgery is total resection to minimize the risk of recurrence. In this case report, a 5-year old boy who had undergone total resection of a posterior fossa pilocytic cerebellar astrocytoma (as documented by a contrast-enhanced computed tomography (CT) scan within 24 hours following surgery), developed a massive recurrence of the tumor within four months. Both the initial histology and the sections examined after the second resection revealed features typical for a pilocytic astrocytoma with no suspicion of malignancy. This case is unusual in that it is contrary to other reports suggesting that CT-documented complete surgical resection of pilocytic astrocytomas is without recurrence, and suggests the need for vigilant radiographic and clinical follow-up of these patients even if apparent complete resection of the tumor has been achieved.

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Year:  1996        PMID: 8865002     DOI: 10.1007/bf00177442

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  31 in total

1.  Results of the treatment of children with recurrent gliomas with lomustine and vincristine.

Authors:  I B Lefkowitz; R J Packer; L N Sutton; K R Siegel; D A Bruce; A E Evans; L Schut
Journal:  Cancer       Date:  1988-03-01       Impact factor: 6.860

Review 2.  Malignant transformation of benign cerebellar astrocytoma.

Authors:  A M Schwartz; N R Ghatak
Journal:  Cancer       Date:  1990-01-15       Impact factor: 6.860

3.  [Long term results of cerebellar astrocytoma with special reference to operative procedure and radiotherapy (author's transl)].

Authors:  T Tsuchida; M Fukuda; R Tanaka
Journal:  Neurol Med Chir (Tokyo)       Date:  1982-02       Impact factor: 1.742

4.  Results of post-operative or exclusive radiotherapy in grade I and grade II cerebellar astrocytoma patients.

Authors:  F H Akyol; I L Atahan; F Zorlu; M Gürkaynak; H Alanyali; E Ozyar
Journal:  Radiother Oncol       Date:  1992-04       Impact factor: 6.280

5.  Treatment options and prognosis for multicentric juvenile pilocytic astrocytoma.

Authors:  A N Mamelak; M D Prados; W G Obana; P H Cogen; M S Edwards
Journal:  J Neurosurg       Date:  1994-07       Impact factor: 5.115

6.  Late malignant recurrence of childhood cerebellar astrocytoma.

Authors:  G P Casadei; G L Arrigoni; V D'Angelo; L Bizzozero
Journal:  Clin Neuropathol       Date:  1990 Nov-Dec       Impact factor: 1.368

7.  Long-term prognosis in children with benign cerebellar astrocytoma.

Authors:  F Gjerris; L Klinken
Journal:  J Neurosurg       Date:  1978-08       Impact factor: 5.115

8.  Benign cerebellar astrocytomas of childhood.

Authors:  J H Schneider; C Raffel; J G McComb
Journal:  Neurosurgery       Date:  1992-01       Impact factor: 4.654

9.  Cystic pilocytic astrocytomas of the cerebral hemispheres. Surgical experience with 51 cases and long-term results.

Authors:  L Palma; B Guidetti
Journal:  J Neurosurg       Date:  1985-06       Impact factor: 5.115

10.  Cerebellar gliomas in children.

Authors:  K Winston; F H Gilles; A Leviton; A Fulchiero
Journal:  J Natl Cancer Inst       Date:  1977-04       Impact factor: 13.506

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  2 in total

Review 1.  Management of pilocytic astrocytoma with diffuse leptomeningeal spread: two cases and review of the literature.

Authors:  Henry E Aryan; Hal S Meltzer; Daniel C Lu; Burak M Ozgur; Michael L Levy; Derek A Bruce
Journal:  Childs Nerv Syst       Date:  2004-09-15       Impact factor: 1.475

2.  Clinical review of pediatric pilocytic astrocytomas treated at a tertiary care hospital in Pakistan.

Authors:  Muhib A Khan; Saniya S Godil; Halima Tabani; Sukaina A Panju; Syed A Enam
Journal:  Surg Neurol Int       Date:  2012-08-21
  2 in total

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