Literature DB >> 8861746

The immunomodulatory and antitumor activities of lectins from the mushroom Tricholoma mongolicum.

H X Wang1, W K Liu, T B Ng, V E Ooi, S T Chang.   

Abstract

TML-1 and TML-2 were two lectins isolated from the mushroom Tricholoma mongolicum. They did not differ appreciably in their pH stability and cationic requirement for hemagglutinating activity. They both stimulated the production of nitrite ions and activated the macrophages in mice. The two lectins were able to inhibit the growth of implanted sarcoma 180 cells by 68.84% and 92.39% respectively. The growth of tumor cells in the mouse peritoneal cavity was also inhibited by the two lectins with TML-2 expressing a greater potency.

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Year:  1996        PMID: 8861746     DOI: 10.1016/0162-3109(95)00049-6

Source DB:  PubMed          Journal:  Immunopharmacology        ISSN: 0162-3109


  23 in total

1.  Musca domestica pupae lectin improves the immunomodulatory activity of macrophages by activating nuclear factor-κB.

Authors:  Xiaohong Cao; Minghui Zhou; Chunling Wang; Lihua Hou; Yuanyuan Li; Linye Chen
Journal:  J Med Food       Date:  2011-12-22       Impact factor: 2.786

2.  A novel lectin from Agrocybe aegerita shows high binding selectivity for terminal N-acetylglucosamine.

Authors:  Shuai Jiang; Yijie Chen; Man Wang; Yalin Yin; Yongfu Pan; Bianli Gu; Guojun Yu; Yamu Li; Barry Hon Cheung Wong; Yi Liang; Hui Sun
Journal:  Biochem J       Date:  2012-04-15       Impact factor: 3.857

3.  AAL exacerbates pro-inflammatory response in macrophages by regulating Mincle/Syk/Card9 signaling along with the Nlrp3 inflammasome assembly.

Authors:  Zhijun Zhang; Long He; Shuang Hu; Yi Wang; Qiaohong Lai; Ping Yang; Qilin Yu; Shu Zhang; Fei Xiong; Sakine Simsekyilmaz; Qin Ning; Jinxiu Li; Dongshan Zhang; Hongliang Zhang; Xudong Xiang; Zhiguang Zhou; Hui Sun; Cong-Yi Wang
Journal:  Am J Transl Res       Date:  2015-10-15       Impact factor: 4.060

4.  A novel lectin with highly potent antiproliferative and HIV-1 reverse transcriptase inhibitory activities from the edible wild mushroom Russula delica.

Authors:  Shuang Zhao; Yongchang Zhao; Shuhong Li; Jingkun Zhao; Guoqing Zhang; Hexiang Wang; Tzi Bun Ng
Journal:  Glycoconj J       Date:  2010-02       Impact factor: 2.916

5.  G₂/M cell cycle arrest by an N-acetyl-D-glucosamine specific lectin from Psathyrella asperospora.

Authors:  Razina Rouf; Alexandre S Stephens; Lina Spaan; Nadia X Arndt; Christopher J Day; Tom W May; Evelin Tiralongo; Joe Tiralongo
Journal:  Glycoconj J       Date:  2013-09-27       Impact factor: 2.916

Review 6.  Opportunistic invasive fungal pathogen Macrophomina phaseolina prognosis from immunocompromised humans to potential mitogenic RBL with an exceptional and novel antitumor and cytotoxic effect.

Authors:  P Arora; N Dilbaghi; A Chaudhury
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-05-08       Impact factor: 3.267

7.  A potent mitogenic lectin from the mycelia of a phytopathogenic fungus, Rhizoctonia bataticola, with complex sugar specificity and cytotoxic effect on human ovarian cancer cells.

Authors:  Nagaraja N Nagre; Vishwanath B Chachadi; Palaniswamy M Sundaram; Ramachandra S Naik; Radha Pujari; Padma Shastry; Bale M Swamy; Shashikala R Inamdar
Journal:  Glycoconj J       Date:  2010-03-22       Impact factor: 2.916

8.  Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum.

Authors:  Igor A Schepetkin; Koffi Kouakou; Ahoua Yapi; Liliya N Kirpotina; Mark A Jutila; Mark T Quinn
Journal:  Int Immunopharmacol       Date:  2013-02-01       Impact factor: 4.932

9.  An antitumour lectin from the edible mushroom Agrocybe aegerita.

Authors:  Chenguang Zhao; Hui Sun; Xin Tong; Yipeng Qi
Journal:  Biochem J       Date:  2003-09-01       Impact factor: 3.857

10.  In vitro and in vivo protective effects of proteoglycan isolated from mycelia of Ganoderma lucidum on carbon tetrachloride-induced liver injury.

Authors:  Xiao-Jun Yang; Jing Liu; Lin-Bai Ye; Fan Yang; Li Ye; Jin-Rong Gao; Zheng-Hui Wu
Journal:  World J Gastroenterol       Date:  2006-03-07       Impact factor: 5.742

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