Literature DB >> 8861464

Onset of diabetes with high titer anti-GAD antibody after IFN therapy for chronic hepatitis.

T Shiba1, Y Morino, K Tagawa, H Fujino, T Unuma.   

Abstract

A case of hyperglycemia induced by the injection of interferon-alpha was experienced in our hospital. This patient showed a sustained high titer of anti-GAD antibody after the onset of diabetes, suggesting that the involvement of immunological disturbance by IFN induces the onset of the disease. However, the susceptibility and the response of the immune system differs from patient to patient, and only limited destruction of beta-cells in the islet of Langerhans and normalization of glucose tolerance by CSII was induced in this patient.

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Year:  1995        PMID: 8861464     DOI: 10.1016/0168-8227(95)01188-9

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  5 in total

Review 1.  Diabetes mellitus during interferon therapy for chronic viral hepatitis.

Authors:  Ali Mofredj; Mehran Howaizi; Denis Grasset; Henri Licht; Sylvie Loison; Bruno Devergie; Renato Demontis; Jean-François Cadranel
Journal:  Dig Dis Sci       Date:  2002-07       Impact factor: 3.199

Review 2.  Hepatitis C virus infection and type 1 and type 2 diabetes mellitus.

Authors:  Alessandro Antonelli; Silvia Martina Ferrari; Dilia Giuggioli; Andrea Di Domenicantonio; Ilaria Ruffilli; Alda Corrado; Silvia Fabiani; Santino Marchi; Clodoveo Ferri; Ele Ferrannini; Poupak Fallahi
Journal:  World J Diabetes       Date:  2014-10-15

Review 3.  Interferon therapy in hepatitis C leading to chronic type 1 diabetes.

Authors:  Taiba Zornitzki; Stephen Malnick; Lyudmila Lysyy; Hilla Knobler
Journal:  World J Gastroenterol       Date:  2015-01-07       Impact factor: 5.742

4.  Type 1 Diabetes Mellitus Associated with Pegylated Interferon-α Plus Ribavirin Treatment for Chronic Hepatitis C: Case Report and Literature Review.

Authors:  Reiko Oka; Naoki Hiroi; Rika Shigemitsu; Mariko Sue; Yasuo Oshima; Mayumi Yoshida-Hiroi
Journal:  Clin Med Insights Endocrinol Diabetes       Date:  2011-08-23

Review 5.  Type I Interferon Is a Catastrophic Feature of the Diabetic Islet Microenvironment.

Authors:  Brittney N Newby; Clayton E Mathews
Journal:  Front Endocrinol (Lausanne)       Date:  2017-09-14       Impact factor: 5.555

  5 in total

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