Literature DB >> 8858516

Study of the antioxidant enzymes in human brain tumors.

P Y Pu1, J Lan, S B Shan, E Q Huang, Y Bai, Y Guo, D H Jiang.   

Abstract

The activities of antioxidant enzymes i.e. Cu, Zn-SOD, Mn-SOD, CAT, and GSH-Px in the normal brain and brain tumors, as well as the two varieties of SOD in the mitochondria were examined and correlated to the histopathological diagnosis and the degree of malignancy of tumors. It was found that these scavenging enzymes of oxygen free radicals were expressed with great regularity in brain tumors. Both Cu, Zn-SOD and Mn-SOD were decreased in descending order in meningiomas, low grade astrocytomas, high grade astrocytomas and medulloblastomas. Furthermore, the reduction of Mn-SOD in mitochondria was proportionate to that of the whole tissues. While in contrast to the SODs, the CAT levels were significantly increased in ascending order in high grade astrocytomas, low grade astrocytomas and meningiomas. GSH-Px increased in meningiomas but not in gliomas.

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Year:  1996        PMID： 8858516     DOI： 10.1007/bf00182134

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  10 in total

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  10 in total
  10 in total

1.  Effects of toxic doses of glutamate on Cu-Zn and Mn/superoxide dismutases activities in human glioma cell lines.

Authors:  Andrea Regner; Daniel Pretto Schunemann; Ivana Grivicich; Celito Luis Diel; Caroline Brunetto Farias; Giovana Kowaleski; Edlaine Mondadori; Gilberto Schwartsmann; Adriana Brondani da Rocha
Journal:  J Neurooncol       Date:  2005-01       Impact factor: 4.130

Review 2.  Circadian rhythm connections to oxidative stress: implications for human health.

Authors:  Melissa Wilking; Mary Ndiaye; Hasan Mukhtar; Nihal Ahmad
Journal:  Antioxid Redox Signal       Date:  2013-04-24       Impact factor: 8.401

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Journal:  J Neurooncol       Date:  2007-05-09       Impact factor: 4.130

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Authors:  Taner Tanriverdi; Hakan Hanimoglu; Tibet Kacira; Galip Zihni Sanus; Rahsan Kemerdere; Pinar Atukeren; Koray Gumustas; Bulent Canbaz; Mehmet Yasar Kaynar
Journal:  J Cancer Res Clin Oncol       Date:  2007-04-25       Impact factor: 4.553

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Authors:  Dora Il'yasova; Jennifer E Marcello; Lucie McCoy; Terri Rice; Margaret Wrensch
Journal:  Cancer Causes Control       Date:  2009-04-12       Impact factor: 2.506

7.  Comparative analysis of antioxidative systems in malignant and benign brain tumours.

Authors:  Vojislav Bogosavljević; Milica Bajčetić; Ivan Spasojević
Journal:  Redox Rep       Date:  2014-09-23       Impact factor: 4.412

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Authors:  Pameeka S Smith-Pearson; Mitra Kooshki; Douglas R Spitz; Leslie B Poole; Weiling Zhao; Mike E Robbins
Journal:  Free Radic Biol Med       Date:  2008-07-27       Impact factor: 7.376

9.  1'-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression.

Authors:  Musa Williams; Illya Tietzel; Quincy A Quick
Journal:  Oncol Lett       Date:  2013-04-05       Impact factor: 2.967

10.  Biochemical and cytogenetic analysis of brain tissues in different grades of glioma patients.

Authors:  Mahalakshmi Palani; R Arunkumar; Vanisree Arambakkam Janardhanam
Journal:  Ann Neurosci       Date:  2010-07
  10 in total

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