Literature DB >> 885842

Polyamines in trypanosomatids.

C J Bacchi, G Y Lipschik, H C Nathan.   

Abstract

Polyamines were determined by n-butanol extraction and thin-layer chromatography in four trypanosomatids: Trypanosoma brucei (rat infection) and cultures of Crithidia fasciculata, Leptomonas sp., and Trypanosoma mega. All had putrescine and spermidine but no detectable spermine. Putrescine and spermidine levels were quantitated for extracts of leptomonas during the normal growth cycle. Spermidine values peaked 18 h before peak cell populations. Spermidine-putrescine ratios for all organisms were related to the presumed phylogeny of the group.

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Year:  1977        PMID: 885842      PMCID: PMC235476          DOI: 10.1128/jb.131.2.657-661.1977

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  22 in total

1.  Polyamine and magnesium contents and polypeptide synthesis as a function of cell growth.

Authors:  K Igarashi; K Hara; Y Watanabe; S Hirose; Y Takeda
Journal:  Biochem Biophys Res Commun       Date:  1975-01-02       Impact factor: 3.575

2.  Polyamines: a high correlation with cell replication.

Authors:  O Heby; L J Marton; C B Wilson; H M Martinez
Journal:  FEBS Lett       Date:  1975-01-15       Impact factor: 4.124

3.  Biosynthesis and metabolism of polyamines and S-adenosylmethionine in the rat.

Authors:  A Raina; T Eloranta; O Kajander
Journal:  Biochem Soc Trans       Date:  1976       Impact factor: 5.407

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Analysis of polyamines by thin-layer chromatography.

Authors:  J E Hammond; E J Herbst
Journal:  Anal Biochem       Date:  1968-03       Impact factor: 3.365

6.  Absence of spermine in filamentous fungi.

Authors:  K W Nickerson; L D Dunkle; J L Van Etten
Journal:  J Bacteriol       Date:  1977-01       Impact factor: 3.490

Review 7.  The oxidation of polyamines in higher plants.

Authors:  T A Smith
Journal:  Xenobiotica       Date:  1971 Jul-Oct       Impact factor: 1.908

8.  Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.

Authors:  S M Lanham; D G Godfrey
Journal:  Exp Parasitol       Date:  1970-12       Impact factor: 2.011

9.  Oxidation of spermidine and spermine in rat liver: purification and properties of polyamine oxidase.

Authors:  E Hölttä
Journal:  Biochemistry       Date:  1977-01-11       Impact factor: 3.162

10.  Diacridines: bifunctional intercalators. II. The biological effects of putrescine, sperimidine and spermine diacridines on HeLa cells and on the L-1210 and P-388 leukemia cells.

Authors:  E S Canellakis; R A Bellantone
Journal:  Biochim Biophys Acta       Date:  1976-02-05
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  2 in total

1.  Polyamines of Anacystis nidulans and metabolism of exogenous spermidine and spermine.

Authors:  S Ramakrishna; L Guarino; S S Cohen
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

2.  Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis.

Authors:  Robert H Barker; Hanlan Liu; Bradford Hirth; Cassandra A Celatka; Richard Fitzpatrick; Yibin Xiang; Erin K Willert; Margaret A Phillips; Marcel Kaiser; Cyrus J Bacchi; Aixa Rodriguez; Nigel Yarlett; Jeffrey D Klinger; Edmund Sybertz
Journal:  Antimicrob Agents Chemother       Date:  2009-03-16       Impact factor: 5.191

  2 in total

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