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Literature DB >> 885735

Substance P and 5-HT in granules isolated from an intestinal argentaffin carcinoid.

J Alumets, R Håkanson, S Ingemansson, F Sundler.

Abstract

Intestinal argentaffin carcinoids, thought to originate from enterochromaffin cells, occasionally contain large amounts of substance P-like immunoreactivity in addition to 5-HT. The cytoplasmic granules of one such tumour were isolated. The granules, which in the electron microscope were shown to be argentaffin, contained both substance P-like immunoreactivity and 5-HT. The results support the view that substance P is localized in a population of enterochromaffin cells where it is stored in the cytoplasmic granules together with 5-HT.

Entities: Disease Gene

Mesh：

Substances：
Serotonin
Substance P

Year: 1977 PMID： 885735 DOI： 10.1007/bf00495858

Source DB: PubMed Journal: Histochemistry ISSN： 0301-5564

11 in total

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Authors: G Nilsson; B Pernow; G H Fischer; K Folkers
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Journal: Anat Anz Date: 1964-07-31

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Authors: A G Pearse; J M Polak; C Adams; P A Kendall
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Journal: Fed Proc Date: 1973-07

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Authors: M Vialli; G Prenna
Journal: J Histochem Cytochem Date: 1969-05 Impact factor: 2.479

7. Immunocytochemical localization of substance P in mammalian intestine.

Authors: A G Pearse; J M Polak
Journal: Histochemistry Date: 1975

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Authors: G Nilsson; L I Larsson; R Håkanson; E Brodin; B Pernow; F Sundler
Journal: Histochemistry Date: 1975

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Authors: P Heitz; J M Polak; D M Timson; A G Pearse
Journal: Histochemistry Date: 1976-11-12

10. Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit.

Authors: A H COONS; E H LEDUC; J M CONNOLLY
Journal: J Exp Med Date: 1955-07-01 Impact factor: 14.307

18 in total

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Review 2. Tubulovillous adenoma of the duodenum: a new etiology for flushing and urinary 5-HIAA elevation.

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3. Pre-treatment with somatostatin in the anaesthetic management of a patient with carcinoid syndrome.

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Journal: Can J Anaesth Date: 1988-07 Impact factor: 5.063

4. The pentagastrin test in the diagnosis of the carcinoid syndrome. Blockade of gastrointestinal symptoms by ketanserin.

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5. Substance P in the argentaffin carcinoid of the caecum: biochemical and biological characterization.

Authors: M Ratzenhofer; R Gamse; H Höfler; L Auböck; H Popper; P Pohl; F Lembeck
Journal: Virchows Arch A Pathol Anat Histol Date: 1981

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Authors: P Skrabanek; D Cannon; J Kirrane; D Powell
Journal: Ir J Med Sci Date: 1978-02 Impact factor: 1.568

7. Glucagon-, glicentin-, and pancreatic polypeptide-like immunoreativities in rectal carcinoids and related colorectal cells.

Authors: R Fiocca; C Capella; R Buffa; R Fontana; E Solcia; E Hage; R E Chance; A J Moody
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