K M Rankin1, R D Mattes. 1. Monell Chemical Senses Center, Philadelphia, PA 19104-3308, USA.
Abstract
OBJECTIVE: To investigate the chemosensory function and food attribute preferences of individuals with Prader-Willi Syndrome. DESIGN: Cross-sectional, matched-groups comparison. SUBJECTS: Fifteen (eight female and seven male) individuals with Prader-Willi Syndrome and an age- and sex-matched non-affected sample. MEASUREMENTS: Intensity ratings of taste and odor stimuli and hedonic ranking of 20 foods varying in sensory attributes (e.g. taste familiarity). RESULTS: Sensory test performance was comparable in the PWS and control groups. In addition, individuals with Prader-Willi Syndrome showed a pattern of food preferences that was similar to their non-affected counterparts. CONCLUSION: Abnormal chemosensory function does not underlie the ingestive behavior of individuals with Prader-Willi Syndrome.
OBJECTIVE: To investigate the chemosensory function and food attribute preferences of individuals with Prader-Willi Syndrome. DESIGN: Cross-sectional, matched-groups comparison. SUBJECTS: Fifteen (eight female and seven male) individuals with Prader-Willi Syndrome and an age- and sex-matched non-affected sample. MEASUREMENTS: Intensity ratings of taste and odor stimuli and hedonic ranking of 20 foods varying in sensory attributes (e.g. taste familiarity). RESULTS: Sensory test performance was comparable in the PWS and control groups. In addition, individuals with Prader-Willi Syndrome showed a pattern of food preferences that was similar to their non-affected counterparts. CONCLUSION: Abnormal chemosensory function does not underlie the ingestive behavior of individuals with Prader-Willi Syndrome.