OBJECTIVE: To determine the age- and gender-related incidence of chronic renal failure in a French urban area. METHODS: Prospective study of adult patients newly identified as having established, chronic renal failure defined by serum creatinine (Scr) > or = 200 mumol/l, with the cooperation of all nephrology and dialysis units in the Ile de France district (10,660,000 inhabitants) during a 1-year period. RESULTS: 2775 patients (1780 males, 995 females) were referred with Scr > or = 200 mumol/l between July 1991 and June 1992, an overall incidence of 260/million population. 847 had advanced renal failure (Scr > or = 500 mumol/l) and 541 patients (19.5%) were > or = 75 years of age. The age-related incidence was 92, 264, 523 and 619/million population in the age groups 20-39, 40-59, 60-74 and > or = 75 years old, respectively. The annual incidence was twice as high in males than in females up to 75 years and three times as high in patients > or = 75 years (1124 vs 356/million population). Based on the proportion of patients reaching end-stage renal failure within one year of referral, the minimal estimation of the need for supportive therapy is 81/million/year. CONCLUSIONS: This epidemiological study in a large French urban area indicates an incidence of 260 patients per million population annually referred to nephrology units for chronic renal failure defined by Scr > or = 200 mumol/l, with a marked preponderance of males and a dramatic increase of incidence with age in both genders.
OBJECTIVE: To determine the age- and gender-related incidence of chronic renal failure in a French urban area. METHODS: Prospective study of adult patients newly identified as having established, chronic renal failure defined by serum creatinine (Scr) > or = 200 mumol/l, with the cooperation of all nephrology and dialysis units in the Ile de France district (10,660,000 inhabitants) during a 1-year period. RESULTS: 2775 patients (1780 males, 995 females) were referred with Scr > or = 200 mumol/l between July 1991 and June 1992, an overall incidence of 260/million population. 847 had advanced renal failure (Scr > or = 500 mumol/l) and 541 patients (19.5%) were > or = 75 years of age. The age-related incidence was 92, 264, 523 and 619/million population in the age groups 20-39, 40-59, 60-74 and > or = 75 years old, respectively. The annual incidence was twice as high in males than in females up to 75 years and three times as high in patients > or = 75 years (1124 vs 356/million population). Based on the proportion of patients reaching end-stage renal failure within one year of referral, the minimal estimation of the need for supportive therapy is 81/million/year. CONCLUSIONS: This epidemiological study in a large French urban area indicates an incidence of 260 patients per million population annually referred to nephrology units for chronic renal failure defined by Scr > or = 200 mumol/l, with a marked preponderance of males and a dramatic increase of incidence with age in both genders.
Authors: Francesco Pizzarelli; Fulvio Lauretani; Stefania Bandinelli; Gwen B Windham; Anna Maria Corsi; Sandra V Giannelli; Luigi Ferrucci; Jack M Guralnik Journal: Nephrol Dial Transplant Date: 2008-11-06 Impact factor: 5.992
Authors: Marko Škrtić; Yuliya Lytvyn; Petter Bjornstad; Heather N Reich; James W Scholey; Paul Yip; Etienne B Sochett; Bruce Perkins; David Z I Cherney Journal: Am J Physiol Renal Physiol Date: 2016-12-28
Authors: Robert A Phillips; Marquetta Faulkner; Jennifer Gassman; Luzmaria Jaen; John W Kusek; Keith Norris; Akinlolu Ojo Journal: J Clin Hypertens (Greenwich) Date: 2004-08 Impact factor: 3.738