| Literature DB >> 885562 |
L S McKenzie, B A Horsburgh, P Ghosh, T K Taylor.
Abstract
An organ culture system is described for adult human articular cartilage obtained from joints after femoral head replacement operations. Cartilage slices maintain maximal viability for 2 days in culture as assessed by uptake of [3H]uridine and [3H]leucine into whole tissue, and 35SO4 into sulphated glycosaminoglycans (GAGs). Since GAGs are the components of cartilage matrix, the depletion of which is associated with osteoarthrosis, a method for measuring sulphated GAG synthesis in culture has been investigated.Entities:
Mesh:
Substances:
Year: 1977 PMID: 885562 DOI: 10.1007/bf02615102
Source DB: PubMed Journal: In Vitro ISSN: 0073-5655