H G Saravelos1, T C Li. 1. Department of Obstetrics and Gynaecology and Biomedical Research Unit, Jessop Hospital for Women, Sheffield, England.
Abstract
OBJECTIVE: To evaluate physical barriers in adhesion prevention. STUDY DESIGN: Literature search. RESULTS: Although numerous adjuvants have been used to prevent or reduce postoperative adhesions, they are by no means a panacea, and research on new synthetic adhesion barriers continues. CONCLUSION: Preliminary data from animal studies indicate that biocompatible, absorbable gel barriers are safe and effective. These agents are easy to apply and readily conform to irregular tissue shapes without fixation. We await the results of future clinical studies.
OBJECTIVE: To evaluate physical barriers in adhesion prevention. STUDY DESIGN: Literature search. RESULTS: Although numerous adjuvants have been used to prevent or reduce postoperative adhesions, they are by no means a panacea, and research on new synthetic adhesion barriers continues. CONCLUSION: Preliminary data from animal studies indicate that biocompatible, absorbable gel barriers are safe and effective. These agents are easy to apply and readily conform to irregular tissue shapes without fixation. We await the results of future clinical studies.
Authors: Yoon Yeo; Taichi Ito; Evangelia Bellas; Christopher B Highley; Robert Marini; Daniel S Kohane Journal: Ann Surg Date: 2007-05 Impact factor: 12.969