Literature DB >> 8853291

Calcitonin gene-related peptide: vasoactive effects and potential therapeutic role.

S D Brain1, H Cambridge.   

Abstract

1. The cardiovascular biology of calcitonin gene-related peptide (CGRP) and the structurally related peptides amylin and adrenomedullin are briefly reviewed. 2. CGRP is a potent and long-lasting vasodilator; its possible role in disease, and the therapeutic potential of CGRP receptor agonists and antagonists is discussed.

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Year:  1996        PMID： 8853291     DOI： 10.1016/0306-3623(95)00125-5

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN： 0306-3623


  19 in total

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Review 2.  CGRP receptor antagonism and migraine.

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3.  Central and peripheral anti-inflammatory effects of maprotiline on carrageenan-induced paw edema in rats.

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4.  Olcegepant blocks neurogenic and non-neurogenic CGRPergic vasodepressor responses and facilitates noradrenergic vasopressor responses in pithed rats.

Authors:  V H Avilés-Rosas; E Rivera-Mancilla; B A Marichal-Cancino; G Manrique-Maldonado; A H Altamirano-Espinoza; A Maassen Van Den Brink; C M Villalón
Journal:  Br J Pharmacol       Date:  2017-05-02       Impact factor: 8.739

5.  Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist.

Authors:  H Doods; G Hallermayer; D Wu; M Entzeroth; K Rudolf; W Engel; W Eberlein
Journal:  Br J Pharmacol       Date:  2000-02       Impact factor: 8.739

Review 6.  Calcitonin gene-related peptide (CGRP) and the pathophysiology of headache: therapeutic implications.

Authors:  L Edvinsson
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

Review 7.  Perivascular innervation: a multiplicity of roles in vasomotor control and myoendothelial signaling.

Authors:  Erika B Westcott; Steven S Segal
Journal:  Microcirculation       Date:  2013-04       Impact factor: 2.628

8.  Role of calcitonin gene-related peptide (CGRP) in ovine burn and smoke inhalation injury.

Authors:  Matthias Lange; Perenlei Enkhbaatar; Daniel L Traber; Robert A Cox; Sam Jacob; Babu P Mathew; Atsumori Hamahata; Lillian D Traber; David N Herndon; Hal K Hawkins
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9.  Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema.

Authors:  J Morgenweck; O S Abdel-Aleem; K C McNamara; R R Donahue; M Z Badr; B K Taylor
Journal:  Neuropharmacology       Date:  2009-11-03       Impact factor: 5.250

10.  Calcitonin gene-related peptide and thermal injury: review of literature.

Authors:  Giulio Gherardini; Giuseppe Curinga; Giuseppe Colella; Nicola Freda; Raffaele Rauso
Journal:  Eplasty       Date:  2009-07-28
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