Literature DB >> 8853178

An atypical psoriatic spondylitis case, successfully treated with methotrexate.

C Tüzün1, O Peker, F Küçüktaş, S Gülbahar, I Kovanlikaya, S Füzün.   

Abstract

We present a 45-year-old male patient who was hospitalized with lumbar disc herniation and whose control magnetic resonance imaging (MRI) findings initially suggested brucella spondylitis. Definitive diagnosis, however, indicated psoriatic spondylitis and the patient was successfully treated with methotrexate. A diagnosis of lumbar disc herniation was made in May 1991, during his psoriasis vulgaris treatment. He was hospitalized in August 1994 with a complaint of low-back pain persisting over the last six months despite treatment with analgesics. He was evaluated by clinical, radiological, laboratory and scintigraphic methods, following control MRI findings suggesting infection of vertebral bodies, particularly pointing to brucellosis in addition to disc herniation. A diagnosis of psoriatic spondylitis was finally established and 7.5 mg methotrexate weekly was administered. Significant improvement was obtained of psoriatic skin lesions, low-back pain and MRI findings through a six-month treatment period.

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Year:  1996        PMID: 8853178     DOI: 10.1007/bf02230367

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  15 in total

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8.  Psoriatic arthritis: clinical response and side effects to methotrexate therapy.

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10.  Articular involvement in human brucellosis: a retrospective analysis of 304 cases.

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Journal:  Semin Arthritis Rheum       Date:  1982-11       Impact factor: 5.532

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  2 in total

Review 1.  MRI in psoriatic arthritis: insights into pathogenesis and treatment response.

Authors:  Fiona M McQueen; Nicola Dalbeth; Anthony Doyle
Journal:  Curr Rheumatol Rep       Date:  2008-08       Impact factor: 4.592

Review 2.  Magnetic resonance imaging in psoriatic arthritis: a review of the literature.

Authors:  Fiona McQueen; Marissa Lassere; Mikkel Østergaard
Journal:  Arthritis Res Ther       Date:  2006-03-23       Impact factor: 5.156

  2 in total

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