Literature DB >> 8852399

Molecular pathology of low grade malignant lymphomas.

H Ratech1.   

Abstract

During the last ten years the combined efforts of pathologists and molecular biologists have helped define several new lymphoma diagnostic categories. In particular, the recognition of chromosomal translocations which have activated the BCL1 and BCL2 proto-oncogenes have strong associations with specific types of non-Hodgkin's malignant lymphomas such as mantle cell lymphoma and follicular center cell lymphoma, respectively. This review will attempt to summarize our current understanding regarding the contributions of BCL1 and BCL2 to lymphomagenesis and diagnosis.

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Year:  1995        PMID: 8852399     DOI: 10.1007/bf01571194

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


  98 in total

1.  Cell cycle analysis of p26-BCL-2 protein levels in proliferating lymphoma and leukemia cell lines.

Authors:  J C Reed; S Tanaka; M Cuddy
Journal:  Cancer Res       Date:  1992-05-15       Impact factor: 12.701

2.  bcl-2 protein expression and correlation with the interchromosomal 14;18 translocation in cutaneous lymphomas and pseudolymphomas.

Authors:  L Cerroni; M Volkenandt; E Rieger; H P Soyer; H Kerl
Journal:  J Invest Dermatol       Date:  1994-02       Impact factor: 8.551

3.  Ultrastructural localization of bcl-2 protein.

Authors:  P Monaghan; D Robertson; T A Amos; M J Dyer; D Y Mason; M F Greaves
Journal:  J Histochem Cytochem       Date:  1992-12       Impact factor: 2.479

4.  Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells.

Authors:  M Pettersson; H Jernberg-Wiklund; L G Larsson; C Sundström; I Givol; Y Tsujimoto; K Nilsson
Journal:  Blood       Date:  1992-01-15       Impact factor: 22.113

5.  Regulation of p26-bcl-2 protein levels in human peripheral blood lymphocytes.

Authors:  J C Reed; T Miyashita; M Cuddy; D Cho
Journal:  Lab Invest       Date:  1992-10       Impact factor: 5.662

6.  Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation.

Authors:  Y Tsujimoto; E Jaffe; J Cossman; J Gorham; P C Nowell; C M Croce
Journal:  Nature       Date:  1985 May 23-29       Impact factor: 49.962

7.  Sequential high-dose therapy with peripheral-blood progenitor-cell support in low-grade non-Hodgkin's lymphoma.

Authors:  R Haas; M Moos; A Karcher; R Möhle; B Witt; H Goldschmidt; S Frühauf; M Flentje; M Wannenmacher; W Hunstein
Journal:  J Clin Oncol       Date:  1994-08       Impact factor: 44.544

8.  Bcl-2 gene rearrangements in primary B-cell lymphoma of the gastrointestinal tract reveal follicular lymphoma as a subtype.

Authors:  C Straka; B Mielke; A Eichelmann; I Trede; A D Ho; P Möller
Journal:  Leukemia       Date:  1993-02       Impact factor: 11.528

9.  CD5-expressing B-cell non-Hodgkin's lymphomas with bcl-1 gene rearrangement have a relatively homogeneous immunophenotype and are associated with an overall poor prognosis.

Authors:  G H Segal; A S Masih; A C Fox; T Jorgensen; M Scott; R C Braylan
Journal:  Blood       Date:  1995-03-15       Impact factor: 22.113

10.  bcl-2 gene rearrangement analysis of Japanese follicular lymphomas by polymerase chain reaction in formalin-fixed, paraffin-embedded tissue specimens.

Authors:  S Mitani; N Aoki; S Mizutani; M Fujiwara; T Kitagawa; T Uehara; S Mori
Journal:  Jpn J Cancer Res       Date:  1993-01
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