| Literature DB >> 8847954 |
H Kanazawa1, N Kurihara, K Hirata, H Fujiwara, T Takeda.
Abstract
Angiotensin II (Ang II) and nitric oxide (NO) regulate a variety of physiological functions. In this study, we suggest that inhaled Ang II produces an initial bronchodilation apparently by stimulating NO production via AT1 receptors. Also, we demonstrate that following the initial bronchodilation, Ang II causes bronchoconstriction in the guinea pig, also via AT1 receptors. Both of the findings are important for our understanding of airway functions induced by Ang II.Entities:
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Year: 1995 PMID： 8847954 DOI： 10.1016/0024-3205(95)00094-1
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037