Literature DB >> 8847530

Detection of measles virus nucleoprotein mRNA in autopsied brain tissues.

Y Katayama1, H Hotta, A Nishimura, Y Tatsuno, M Homma.   

Abstract

By means of RT-PCR, a portion of measles virus (MV) mRNA encoding nucleoprotein (NP) could be detected in 11 (18%) of 61 brain tissue samples obtained from administrative autopsy cases, who apparently had not suffered from subacute sclerosing panencephalitis (SSPE)-like central nervous system disorders. Most of the brain-derived NP sequences showed significant asynonymous nucleotide substitutions when compared with wild-type MV isolates and SSPE virus. Our present results suggest that MV commonly persists in the human brain without causing apparent clinical symptoms, probably due to decreased virus replication.

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Year:  1995        PMID： 8847530     DOI： 10.1099/0022-1317-76-12-3201

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  29 in total

Review 1.  On immunological memory.

Authors:  R M Zinkernagel
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2000-03-29       Impact factor: 6.237

2.  T cell-, interleukin-12-, and gamma interferon-driven viral clearance in measles virus-infected brain tissue.

Authors:  Samantha R Stubblefield Park; Mi Widness; Alan D Levine; Catherine E Patterson
Journal:  J Virol       Date:  2011-01-26       Impact factor: 5.103

Review 3.  Immunological memory ≠ protective immunity.

Authors:  Rolf M Zinkernagel
Journal:  Cell Mol Life Sci       Date:  2012-04-06       Impact factor: 9.261

4.  hsp72, a host determinant of measles virus neurovirulence.

Authors:  Thomas Carsillo; Zachary Traylor; Changsun Choi; Stefan Niewiesk; Michael Oglesbee
Journal:  J Virol       Date:  2006-09-13       Impact factor: 5.103

Review 5.  Measles virus, immune control, and persistence.

Authors:  Diane E Griffin; Wen-Hsuan Lin; Chien-Hsiung Pan
Journal:  FEMS Microbiol Rev       Date:  2012-03-13       Impact factor: 16.408

6.  On the role of antigen in maintaining cytotoxic T-cell memory.

Authors:  T M Kündig; M F Bachmann; S Oehen; U W Hoffmann; J J Simard; C P Kalberer; H Pircher; P S Ohashi; H Hengartner; R M Zinkernagel
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-03       Impact factor: 11.205

7.  Molecular epidemiology and changing distribution of genotypes of measles virus field strains in Japan.

Authors:  Y Katayama; K Shibahara; T Kohama; M Homma; H Hotta
Journal:  J Clin Microbiol       Date:  1997-10       Impact factor: 5.948

Review 8.  Keeping it in check: chronic viral infection and antiviral immunity in the brain.

Authors:  Katelyn D Miller; Matthias J Schnell; Glenn F Rall
Journal:  Nat Rev Neurosci       Date:  2016-11-04       Impact factor: 34.870

9.  Detection and comparative analysis of persistent measles virus infection in Crohn's disease by immunogold electron microscopy.

Authors:  P Daszak; M Purcell; J Lewin; A P Dhillon; R E Pounder; A J Wakefield
Journal:  J Clin Pathol       Date:  1997-04       Impact factor: 3.411

10.  Immune response-mediated protection of adult but not neonatal mice from neuron-restricted measles virus infection and central nervous system disease.

Authors:  D M Lawrence; M M Vaughn; A R Belman; J S Cole; G F Rall
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103
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