Literature DB >> 884693

Role of drug concentration, duration of exposure, and endogenous metabolites in determining methotrexate cytotoxicity.

H M Pinedo, B A Chabner.   

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Year:  1977        PMID: 884693

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


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  19 in total

1.  Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial.

Authors:  Torben S Mikkelsen; Alex Sparreboom; Cheng Cheng; Yinmei Zhou; James M Boyett; Susana C Raimondi; John C Panetta; W Paul Bowman; John T Sandlund; Ching-Hon Pui; Mary V Relling; William E Evans
Journal:  J Clin Oncol       Date:  2011-03-28       Impact factor: 44.544

2.  Pharmacokinetic monitoring of high-dose methotrexate. Early recognition of high-risk patients.

Authors:  W E Evans; C B Pratt; R H Taylor; L F Barker; W R Crom
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

3.  An indication of possible impending toxicity during moderately high dose methotrexate infusions.

Authors:  J W Paxton; E J Stephens; H F Wood
Journal:  Br J Clin Pharmacol       Date:  1978-12       Impact factor: 4.335

4.  Methotrexate administered by 6-h and 24-h infusion: a pharmacokinetic comparison.

Authors:  J D Borsi; D Schuler; P J Moe
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

5.  Evaluation of 24-hour infusion of high-dose methotrexate--pharmacokinetics and toxicity.

Authors:  T S Goh; K Y Wong; B Lampkin; J O'Leary; D Gnarra
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

6.  Pharmacokinetic and clinical studies of 24-h infusions of high-dose methotrexate.

Authors:  H J Cohen; N Jaffe
Journal:  Cancer Chemother Pharmacol       Date:  1978       Impact factor: 3.333

7.  Long-duration intracavitary infusion of methotrexate with systemic leucovorin protection in patients with malignant effusions.

Authors:  S B Howell; B B Chu; W E Wung; B M Metha; J Mendelsohn
Journal:  J Clin Invest       Date:  1981-04       Impact factor: 14.808

Review 8.  Pharmacokinetics of anticancer drugs in children.

Authors:  W R Crom; A M Glynn-Barnhart; J H Rodman; M E Teresi; R E Kavanagh; M L Christensen; M V Relling; W E Evans
Journal:  Clin Pharmacokinet       Date:  1987-03       Impact factor: 6.447

9.  Role of culture conditions and exposure duration in determining sensitivity of human bone marrow progenitor cells to methotrexate.

Authors:  G E Umbach; G Spitzer; J A Ajani; V Hug; H Thames; F B Rudolph; B Drewinko
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

10.  Clinical pharmacokinetics of 6-hour infusion of high-dose methotrexate. Preliminary trial of monitoring high infusion doses.

Authors:  M Luyckx; J L Cazin; C Brunet; P Gosselin; M C Demaille
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

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