Literature DB >> 8844130

Isolation and amino acid sequence of a cystatin-type cysteine proteinase inhibitor from bovine hoof.

H Tsushima1, K Higashiyama, H Mine.   

Abstract

A low molecular mass cysteine proteinase inhibitor was found and isolated from bovine hoof. Purification of the inhibitor to homogeneity was performed by carboxymethyl-papain-sepharose affinity and DE-52 ion exchange chromatographies. From 15 g of bovine hoof, 0.25 mg of cysteine proteinase inhibitor was isolated. It had 100 amino acid residues and molecular mass of 11 406 Da, and its N-terminus was blocked. The amino acid sequence of the inhibitor demonstrated high similarity with that of the family 1 group, especially bovine thymus-derived cystatin. Thus, in summary, bovine hoof contains a cystatin-type cysteine proteinase inhibitor, presumably a family 1 cystatin.

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Year:  1996        PMID： 8844130     DOI： 10.1007/bf02505240

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  19 in total

1.  Purification and characterization of a cystatin-type cysteine proteinase inhibitor in the human hair shaft.

Authors:  H Tsushima; A Ueki; H Mine; N Nakajima; H Sumi; V K Hopsu-Havu
Journal:  Arch Dermatol Res       Date:  1992       Impact factor: 3.017

Review 2.  The cystatins: protein inhibitors of cysteine proteinases.

Authors:  V Turk; W Bode
Journal:  FEBS Lett       Date:  1991-07-22       Impact factor: 4.124

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

4.  The low-molecular-weight SH-protease inhibitor in rat skin is epidermal.

Authors:  M Järvinen; O Räsänen; A Rinne
Journal:  J Invest Dermatol       Date:  1978-08       Impact factor: 8.551

5.  A gas-liquid solid phase peptide and protein sequenator.

Authors:  R M Hewick; M W Hunkapiller; L E Hood; W J Dreyer
Journal:  J Biol Chem       Date:  1981-08-10       Impact factor: 5.157

6.  Isolation of cysteine proteinase inhibitor, cystatin A, from human nails.

Authors:  H Tsushima
Journal:  Arch Dermatol Res       Date:  1993       Impact factor: 3.017

7.  Amino acid sequence of rat liver thiol proteinase inhibitor.

Authors:  K Takio; E Kominami; N Wakamatsu; N Katunuma; K Titani
Journal:  Biochem Biophys Res Commun       Date:  1983-09-30       Impact factor: 3.575

8.  Localization of cathepsin H and its inhibitor in the skin and other stratified epithelia.

Authors:  A Rinne; H Kirschke; M Järvinen; V K Hopsu-Havu; B Wiederanders; P Bohley
Journal:  Arch Dermatol Res       Date:  1985       Impact factor: 3.017

9.  Bacterial growth blocked by a synthetic peptide based on the structure of a human proteinase inhibitor.

Authors:  L Björck; P Akesson; M Bohus; J Trojnar; M Abrahamson; I Olafsson; A Grubb
Journal:  Nature       Date:  1989-01-26       Impact factor: 49.962

10.  Cystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum.

Authors:  A Anastasi; M A Brown; A A Kembhavi; M J Nicklin; C A Sayers; D C Sunter; A J Barrett
Journal:  Biochem J       Date:  1983-04-01       Impact factor: 3.857
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