| Literature DB >> 8843686 |
G Hempel1, D Lehmkuhl, S Krümpelmann, G Blaschke, J Boos.
Abstract
A method has been developed for the determination of paclitaxel (Taxol) in plasma and urine using capillary electrophoresis with sodium dodecyl sulfate as additive in the run buffer. The samples are extracted and preconcentrated with tert.-butyl methyl ether. Taxotere has been used as the internal standard. The limit of detection of paclitaxel is 20 ng/ml. In comparison to high-performance liquid chromatography, the capillary electrophoresis method is simple and needs less organic solvents.Entities:
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Year: 1996 PMID： 8843686 DOI： 10.1016/0021-9673(96)00351-2
Source DB: PubMed Journal: J Chromatogr A ISSN： 0021-9673 Impact factor: 4.759