| Literature DB >> 8842581 |
Abstract
The concept of bioavailability is discussed with particular references to the sex steroids. Problems encountered in the measurement of bioavailability of these steroids and the various factors that may affect their bioavailability are briefly described. Information regarding the bioavailability of the estrogens and gestogens, some of which are prodrugs, used in oral contraception and hormone replacement therapy is summarized and the implications regarding the clinical use of these steroids are discussed.Entities:
Keywords: Biology; Contraception; Contraceptive Agents, Estrogen--pharmacodynamics; Contraceptive Agents, Female--pharmacodynamics; Contraceptive Agents, Progestin--pharmacodynamics; Contraceptive Agents--pharmacodynamics; Contraceptive Methods; Endocrine System; Estrogens--pharmacodynamics; Family Planning; Hormone Replacement Therapy; Hormones; Literature Review; Oral Contraceptives; Physiology; Progestational Hormones; Progesterone--pharmacodynamics; Treatment
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Year: 1996 PMID： 8842581 DOI： 10.1016/0010-7824(96)00136-9
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375