| Literature DB >> 884095 |
Abstract
The Na+/K+ pump on the apical membrane of the choroid plexus epithelium was found to be sensitive to bicarbonate. Glycodiazine, a non-volatile, lipid soluble buffer with a pK of 5.7, mimicked the effect of bicarbonate, and was transported across the epithelium in the same direction as sodium. These results are explained in terms of a Na+/H+ exchange mechanism on the basal-lateral membrane.Entities:
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Year: 1977 PMID： 884095 DOI： 10.1016/0005-2736(77)90297-8
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002