Literature DB >> 8840023

Localization of GABAA alpha 1 mRNA subunit in the brainstem nuclei controlling esophageal peristalsis.

D L Broussard1, X Li, S M Altschuler.   

Abstract

The nucleus of the solitary tract, the site of esophageal premotor neurons (PMN), is tonically inhibited by GABAergic neurons via the GABAA receptor. We investigated the expression of GABAA alpha 1 subunit mRNA within esophageal PMNs of the NTS utilizing transynaptic tracing with pseudorabies virus and nonisotopic in-situ hybridization. Double-labeling studies revealed that the majority of PRV-immunoreactive cells also expressed GABAA alpha 1 mRNA. The expression of GABAA subunits supports a role for GABA in the brainstem circuit controlling esophageal peristalsis.

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Year:  1996        PMID： 8840023     DOI： 10.1016/0169-328x(96)00080-0

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  4 in total

1.  Local circuit input to the medullary reticular formation from the rostral nucleus of the solitary tract.

Authors:  J Nasse; D Terman; S Venugopal; G Hermann; R Rogers; J B Travers
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2008-08-20       Impact factor: 3.619

2.  GABA(A) receptor epsilon-subunit may confer benzodiazepine insensitivity to the caudal aspect of the nucleus tractus solitarii of the rat.

Authors:  S Kasparov; K A Davies; U A Patel; P Boscan; M Garret; J F Paton
Journal:  J Physiol       Date:  2001-11-01       Impact factor: 5.182

3.  Tonic GABAA receptor-mediated inhibition in the rat dorsal motor nucleus of the vagus.

Authors:  Hong Gao; Bret N Smith
Journal:  J Neurophysiol       Date:  2009-12-16       Impact factor: 2.714

4.  Nucleus of the solitary tract in the C57BL/6J mouse: Subnuclear parcellation, chorda tympani nerve projections, and brainstem connections.

Authors:  Donald Ganchrow; Judith R Ganchrow; Vanessa Cicchini; Dianna L Bartel; Daniel Kaufman; David Girard; Mark C Whitehead
Journal:  J Comp Neurol       Date:  2014-05-01       Impact factor: 3.215
  4 in total

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