STUDY DESIGN: This retrospective study reviewed five patients with scoliosis associated with cerebral gigantism (Sotos syndrome). OBJECTIVE: To clarify the clinical characteristics and progression of scoliosis in patients with cerebral gigantism. SUMMARY OF BACKGROUND DATA. Little has been reported about spinal deformity in this syndrome. METHODS: The records and radiographs of five patients were reviewed. RESULTS: Scoliosis was first noticed at the age of 5 years in one case and at 6-16 months in the others. Their curve patterns were not consistent. Cobb's angles increased rapidly by 4 years of age and after 8 years of age despite attempts at bracing. CONCLUSIONS: Excessive growth in infancy and growth-spurt period after 8 years of age may be related to the rapid progression of scoliosis in the same period.
STUDY DESIGN: This retrospective study reviewed five patients with scoliosis associated with cerebral gigantism (Sotos syndrome). OBJECTIVE: To clarify the clinical characteristics and progression of scoliosis in patients with cerebral gigantism. SUMMARY OF BACKGROUND DATA. Little has been reported about spinal deformity in this syndrome. METHODS: The records and radiographs of five patients were reviewed. RESULTS:Scoliosis was first noticed at the age of 5 years in one case and at 6-16 months in the others. Their curve patterns were not consistent. Cobb's angles increased rapidly by 4 years of age and after 8 years of age despite attempts at bracing. CONCLUSIONS: Excessive growth in infancy and growth-spurt period after 8 years of age may be related to the rapid progression of scoliosis in the same period.