Literature DB >> 8838432

The dilemma of the prolonged QT interval in early drug studies.

M Thomas1, J G Maconochie, E Fletcher.   

Abstract

Mesh:

Year:  1996        PMID: 8838432     DOI: 10.1111/j.1365-2125.1996.tb00163.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


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  6 in total

Review 1.  Preclinical in vitro cardiac electrophysiology: a method of predicting arrhythmogenic potential of antihistamines in humans?

Authors:  I Cavero; M Mestre; J M Guillon; E Heuillet; A G Roach
Journal:  Drug Saf       Date:  1999       Impact factor: 5.606

Review 2.  Potentially significant drug interactions of class III antiarrhythmic drugs.

Authors:  Weeranuj Yamreudeewong; Michael DeBisschop; Linda G Martin; Dennis L Lower
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

Review 3.  Pharmacokinetic-pharmacodynamic modeling in the data analysis and interpretation of drug-induced QT/QTc prolongation.

Authors:  Vladimir Piotrovsky
Journal:  AAPS J       Date:  2005-10-24       Impact factor: 4.009

4.  Designing and interpreting the results of first-time-to-man studies.

Authors:  A A Patat
Journal:  Dialogues Clin Neurosci       Date:  2000-09       Impact factor: 5.986

5.  Methodological considerations in the design of trials for safety assessment of new drugs and chemical entities.

Authors:  Cornel Pater
Journal:  Curr Control Trials Cardiovasc Med       Date:  2005-02-03

6.  Lenalidomide at therapeutic and supratherapeutic doses does not prolong QTc intervals in the thorough QTc study conducted in healthy men.

Authors:  Nianhang Chen; Ying Ye; Liangang Liu; Josephine Reyes; Mahmoud S Assaf; Claudia Kasserra; Simon Zhou; Maria Palmisano
Journal:  Basic Clin Pharmacol Toxicol       Date:  2013-06-20       Impact factor: 4.080

  6 in total

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