Literature DB >> 8837951

The determination of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) in meconium.

C Moore1, D Lewis, J Becker, J Leikin.   

Abstract

The determination of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (THCCOOH), the major urinary metabolite of delta 9-tetrahydrocannabinol (THC), in meconium is extremely difficult because of the high concentration of lipids in the specimen and the low concentration of drug present. A simple, robust, analytical procedure for the screening and confirmation of THCCOOH in meconium is presented. To our knowledge, the procedure is the first published method for the successful confirmation of THCCOOH in meconium and is used routinely in our laboratory for the purpose of detecting marijuana use during pregnancy.

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Year:  1996        PMID: 8837951     DOI: 10.1093/jat/20.1.50

Source DB:  PubMed          Journal:  J Anal Toxicol        ISSN: 0146-4760            Impact factor:   3.367


  3 in total

1.  Prenatal Major Depressive Disorder, Placenta Glucocorticoid and Serotonergic Signaling, and Infant Cortisol Response.

Authors:  Laura R Stroud; George D Papandonatos; Stephanie H Parade; Amy L Salisbury; Maureen G Phipps; Barry M Lester; James F Padbury; Carmen J Marsit
Journal:  Psychosom Med       Date:  2016 Nov/Dec       Impact factor: 4.312

2.  Effect of hydrolysis on identifying prenatal cannabis exposure.

Authors:  Teresa R Gray; Allan J Barnes; Marilyn A Huestis
Journal:  Anal Bioanal Chem       Date:  2010-06-02       Impact factor: 4.142

Review 3.  Pharmacokinetics of Cannabis and Its Derivatives in Animals and Humans During Pregnancy and Breastfeeding.

Authors:  Anaëlle Monfort; Ema Ferreira; Grégoire Leclair; Gregory Anton Lodygensky
Journal:  Front Pharmacol       Date:  2022-07-12       Impact factor: 5.988

  3 in total

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