Literature DB >> 8835576

Temporal association between the use of methotrexate and development of leukemia in 2 patients with rheumatoid arthritis.

L Dubin Kerr1, K Troy, L Isola.   

Abstract

To date only a single case of leukemia coincident with the use of methotrexate (MTX) in rheumatoid arthritis (RA) has been reported. We report 2 additional patients with RA, each of whom developed leukemia after receiving short term low dose MTX. Whether these cases represent an adverse effect of MTX treatment has yet to be determined.

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Year:  1995        PMID： 8835576

Source DB:  PubMed          Journal:  J Rheumatol        ISSN： 0315-162X            Impact factor:   4.666


  6 in total

1.  Development of myeloid sarcoma after long-term methotrexate use for rheumatoid arthritis.

Authors:  Tomomi Sakai; Shinobu Tamura; Takashi Miyoshi; Naofumi Nesumi; Kenichi Nagai; Koichi Oshima
Journal:  Int J Hematol       Date:  2014-02-07       Impact factor: 2.490

Review 2.  Study of eight cases of cancer in 426 rheumatoid arthritis patients treated with methotrexate.

Authors:  C Bologna; M C Picot; C Jorgensen; P Viu; R Verdier; J Sany
Journal:  Ann Rheum Dis       Date:  1997-02       Impact factor: 19.103

Review 3.  Rheumatic diseases and chronic myelogenous leukemia, presentation of four cases and review of the literature.

Authors:  Soner Senel; Emin Kaya; Ismet Aydogdu; M Ali Erkurt; Irfan Kuku
Journal:  Rheumatol Int       Date:  2006-01-11       Impact factor: 2.631

4.  Acute erythroleukemia in a rheumatoid arthritis patient during low-dose methotrexate therapy.

Authors:  Byung-Ryul Choi; Myung-Ju Ahn; Woong Soo Lee; Tae-Hwan Kim; Sang-Cheol Bae; Jae-Bum Jun
Journal:  Rheumatol Int       Date:  2004-08-25       Impact factor: 2.631

5.  A Fatal Case of Acute Myeloid Leukaemia-Methotrexate Related or Primary Autoimmune Disease Related: A Rare Case Report.

Authors:  Saurabh Agarwal; Nidhi Kaeley; Priyanka Gupta; Vibha Gupta; Rohan Bhatia
Journal:  J Clin Diagn Res       Date:  2016-03-01

6.  Acute myeloid leukemia with t(3;21)(q26.2;q22) developing following low-dose methotrexate therapy for rheumatoid arthritis and expressing two AML1/MDS1/EVI1 fusion proteins: A case report.

Authors:  Keisuke Tanaka; Gaku Oshikawa; Hiroki Akiyama; Shinya Ishida; Toshikage Nagao; Masahide Yamamoto; Osamu Miura
Journal:  Oncol Lett       Date:  2017-05-10       Impact factor: 2.967
  6 in total

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