Literature DB >> 8835458

Cytotoxic xanthones from Garcinia hanburyi.

J Asano1, K Chiba, M Tada, T Yoshii.   

Abstract

Eleven novel cytotoxic xanthones, gambogin, morellin dimethyl acetal, isomoreollin B, moreollic acid, gambogenic acid, gambogenin, isogambogenin, desoxygambogenin, gambogenin dimethyl acetal, gambogellic acid and hanburin were isolated together with four known xanthones, gambogic acid, isomorellin, morellic acid and desoxymorellin, from the dry latex of Garcinia hanburyi. The structures were elucidated by a detailed spectroscopic analysis.

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Year:  1996        PMID： 8835458     DOI： 10.1016/0031-9422(95)00682-6

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  24 in total

1.  Unified synthesis of caged Garcinia natural products based on a site-selective Claisen/Diels-Alder/Claisen rearrangement.

Authors:  Eric J Tisdale; Irina Slobodov; Emmanuel A Theodorakis
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-21       Impact factor: 11.205

2.  Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines.

Authors:  Chariya Hahnvajanawong; Wongwarut Boonyanugomol; Tapanawan Nasomyon; Watcharin Loilome; Nisana Namwat; Natthinee Anantachoke; Wichittra Tassaneeyakul; Banchob Sripa; Wises Namwat; Vichai Reutrakul
Journal:  World J Gastroenterol       Date:  2010-05-14       Impact factor: 5.742

Review 3.  Chemistry and biology of the caged Garcinia xanthones.

Authors:  Oraphin Chantarasriwong; Ayse Batova; Warinthorn Chavasiri; Emmanuel A Theodorakis
Journal:  Chemistry       Date:  2010-09-03       Impact factor: 5.236

4.  Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues.

Authors:  Yulin Ren; Susan Matthew; Daniel D Lantvit; Tran Ngoc Ninh; Heebyung Chai; James R Fuchs; Djaja D Soejarto; Esperanza J Carcache de Blanco; Steven M Swanson; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2011-03-23       Impact factor: 4.050

5.  Subcellular localization and activity of gambogic acid.

Authors:  Gianni Guizzunti; Ayse Batova; Oraphin Chantarasriwong; Marianna Dakanali; Emmanuel A Theodorakis
Journal:  Chembiochem       Date:  2012-04-24       Impact factor: 3.164

6.  Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death.

Authors:  Sung-Wuk Jang; Masashi Okada; Iqbal Sayeed; Ge Xiao; Donald Stein; Peng Jin; Keqiang Ye
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-02       Impact factor: 11.205

7.  Caged Garcinia Xanthones, a Novel Chemical Scaffold with Potent Antimalarial Activity.

Authors:  Hangjun Ke; Joanne M Morrisey; Shiwei Qu; Oraphin Chantarasriwong; Michael W Mather; Emmanuel A Theodorakis; Akhil B Vaidya
Journal:  Antimicrob Agents Chemother       Date:  2016-12-27       Impact factor: 5.191

8.  A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid.

Authors:  Shailaja Kasibhatla; Katayoun A Jessen; Sergei Maliartchouk; Jean Yu Wang; Nicole M English; John Drewe; Ling Qiu; Shannon P Archer; Anthony E Ponce; Nilantha Sirisoma; Songchun Jiang; Han-Zhong Zhang; Kurt R Gehlsen; Sui Xiong Cai; Douglas R Green; Ben Tseng
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-15       Impact factor: 11.205

9.  Evaluation of the pharmacophoric motif of the caged Garcinia xanthones.

Authors:  Oraphin Chantarasriwong; Woo Cheal Cho; Ayse Batova; Warinthorn Chavasiri; Curtis Moore; Arnold L Rheingold; Emmanuel A Theodorakis
Journal:  Org Biomol Chem       Date:  2009-09-24       Impact factor: 3.876

10.  The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma.

Authors:  Di He; Qin Xu; Ming Yan; Ping Zhang; Xiaojian Zhou; Zhiyuan Zhang; Wenhu Duan; Laiping Zhong; Dongxia Ye; Wantao Chen
Journal:  BMC Cancer       Date:  2009-09-25       Impact factor: 4.430
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