Literature DB >> 8834900

Clarithromycin in treatment of early Lyme disease: a pilot study.

R J Dattwyler1, E Grunwaldt, B J Luft.   

Abstract

Forty-one patients with erythema migrans were enrolled in an open-labelled pilot study of oral clarithromycin, 500 mg twice daily for 21 days, for the treatment of early Lyme disease. Immediately posttherapy, pretreatment signs and symptoms resolved among 91% of the 33 evaluable patients. At 6 months, all 28 of the evaluable patients were well. Clarithromycin shows promise as an effective agent for the treatment of early Lyme disease and warrants further study.

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Year:  1996        PMID: 8834900      PMCID: PMC163136     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  9 in total

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Journal:  Infect Dis Clin North Am       Date:  1991-03       Impact factor: 5.982

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Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691

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Authors:  B W Berger
Journal:  Semin Dermatol       Date:  1993-12

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Authors:  R C Johnson; C Kodner; M Russell; D Girard
Journal:  J Antimicrob Chemother       Date:  1990-01       Impact factor: 5.790

5.  Comparative antimicrobial activity of the new macrolides against Borrelia burgdorferi.

Authors:  V Preac-Mursic; B Wilske; G Schierz; E Süss; B Gross
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-07       Impact factor: 3.267

6.  Efficacy of clarithromycin for treatment of experimental Lyme disease in vivo.

Authors:  J Alder; M Mitten; K Jarvis; P Gupta; J Clement
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

7.  Antibiotic therapy in early erythema migrans disease and related disorders.

Authors:  K Weber; U Neubert; R Thurmayr
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1987-02

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Authors:  E M Massarotti; S W Luger; D W Rahn; R P Messner; J B Wong; R C Johnson; A C Steere
Journal:  Am J Med       Date:  1992-04       Impact factor: 4.965

9.  Amoxycillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis.

Authors:  R J Dattwyler; D J Volkman; S M Conaty; S P Platkin; B J Luft
Journal:  Lancet       Date:  1990-12-08       Impact factor: 79.321

  9 in total
  7 in total

Review 1.  Evidence assessments and guideline recommendations in Lyme disease: the clinical management of known tick bites, erythema migrans rashes and persistent disease.

Authors:  Daniel J Cameron; Lorraine B Johnson; Elizabeth L Maloney
Journal:  Expert Rev Anti Infect Ther       Date:  2014-07-30       Impact factor: 5.091

Review 2.  Rational prescribing of antibacterials in ambulatory children.

Authors:  J E Hoppe
Journal:  Pharmacoeconomics       Date:  1996-12       Impact factor: 4.981

3.  Solitary erythema migrans in children: comparison of treatment with clarithromycin and amoxicillin.

Authors:  Tea Nizič; Eva Velikanje; Eva Ružić-Sabljić; Maja Arnež
Journal:  Wien Klin Wochenschr       Date:  2012-07-04       Impact factor: 1.704

Review 4.  Choosing the right macrolide antibiotic. A guide to selection.

Authors:  L Charles; J Segreti
Journal:  Drugs       Date:  1997-03       Impact factor: 9.546

Review 5.  Efficacy and Safety of Antibiotic Therapy in Early Cutaneous Lyme Borreliosis: A Network Meta-analysis.

Authors:  Gabriel Torbahn; Heidelore Hofmann; Gerta Rücker; Karin Bischoff; Michael H Freitag; Rick Dersch; Volker Fingerle; Edith Motschall; Joerg J Meerpohl; Christine Schmucker
Journal:  JAMA Dermatol       Date:  2018-11-01       Impact factor: 10.282

Review 6.  Diagnosis, treatment, and prevention of Lyme disease in children.

Authors:  Stephen C Eppes
Journal:  Paediatr Drugs       Date:  2003       Impact factor: 3.022

7.  Evidence of a conjugal erythromycin resistance element in the Lyme disease spirochete Borrelia burgdorferi.

Authors:  Charlene R Jackson; Julie A Boylan; Jonathan G Frye; Frank C Gherardini
Journal:  Int J Antimicrob Agents       Date:  2007-10-01       Impact factor: 5.283

  7 in total

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