Literature DB >> 8833234

A locus on the X chromosome is linked to body length in mice.

A V Lembertas1, J S Fisher, C H Warden, P Z Wen, Y R Xia, A J Lusis.   

Abstract

Linkage between body length (anus to nose (AN) length) and three markers on the mouse X Chromosome was found in an interspecific backcross ((C57BL/6J x Mus spretus) F 1x C57BL/6J), designated BSB. A cross of 409 mice were scored for 148 genetic markers distributed on all chromosomes except the Y Chromosome. Statistical analysis revealed highly significant linkage (LOD score 5.5) between body length and a locus in the middle portion of the X Chromosome, the nearest markers being the microsatellite marker DXMit73 and a farnesyl pyrophosphate locus (Fpsl9) 3.1 cM proximal to DXMit73. The locus explains 10% of the variance in AN length and affects both males and females to about the same extent.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8833234     DOI： 10.1007/s003359900048

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  14 in total

1.  A genetic map of the mouse suitable for typing intraspecific crosses.

Authors:  W Dietrich; H Katz; S E Lincoln; H S Shin; J Friedman; N C Dracopoli; E S Lander
Journal:  Genetics       Date:  1992-06       Impact factor: 4.562

2.  Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.

Authors:  E S Lander; D Botstein
Journal:  Genetics       Date:  1989-01       Impact factor: 4.562

3.  Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.

Authors:  C H Warden; M Mehrabian; K Y He; M Y Yoon; A Diep; Y R Xia; P Z Wen; K L Svenson; R S Sparkes; A J Lusis
Journal:  Genomics       Date:  1993-11       Impact factor: 5.736

4.  Sex chromosome aberrations and stature: deduction of the principal factors involved in the determination of adult height.

Authors:  T Ogata; N Matsuo
Journal:  Hum Genet       Date:  1993-07       Impact factor: 4.132

Review 5.  Genetic dissection of complex traits.

Authors:  E S Lander; N J Schork
Journal:  Science       Date:  1994-09-30       Impact factor: 47.728

6.  New insights into the man-mouse comparative map of the X chromosome.

Authors:  H J Blair; V Reed; S H Laval; Y Boyd
Journal:  Genomics       Date:  1994-01-15       Impact factor: 5.736

7.  Identification of four chromosomal loci determining obesity in a multifactorial mouse model.

Authors:  C H Warden; J S Fisler; S M Shoemaker; P Z Wen; K L Svenson; M J Pace; A J Lusis
Journal:  J Clin Invest       Date:  1995-04       Impact factor: 14.808

8.  Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model.

Authors:  C H Warden; J S Fisler; M J Pace; K L Svenson; A J Lusis
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

9.  MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.

Authors:  E S Lander; P Green; J Abrahamson; A Barlow; M J Daly; S E Lincoln; L A Newberg; L Newburg
Journal:  Genomics       Date:  1987-10       Impact factor: 5.736

10.  Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites.

Authors:  J M Love; A M Knight; M A McAleer; J A Todd
Journal:  Nucleic Acids Res       Date:  1990-07-25       Impact factor: 16.971
View more
  3 in total

1.  Quantitative trait loci affecting body weight and fatness from a mouse line selected for extreme high growth.

Authors:  G A Brockmann; C S Haley; U Renne; S A Knott; M Schwerin
Journal:  Genetics       Date:  1998-09       Impact factor: 4.562

2.  Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice.

Authors:  G A Brockmann; J Kratzsch; C S Haley; U Renne; M Schwerin; S Karle
Journal:  Genome Res       Date:  2000-12       Impact factor: 9.043

3.  Mapping genetic loci that interact with myostatin to affect growth traits.

Authors:  Y Cheng; S Rachagani; J C M Dekkers; M S Mayes; R Tait; J M Reecy
Journal:  Heredity (Edinb)       Date:  2011-06-22       Impact factor: 3.821
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.