Literature DB >> 8832463

Strategies in the treatment of diffuse pontine gliomas: the therapeutic role of hyperfractionated radiotherapy and chemotherapy.

M T Jennings1, M L Freeman, M J Murray.   

Abstract

This article will review the current treatment of pediatric patients with diffuse pontine gliomas (DPG) and discuss three potential avenues of therapeutic research including (i) radiotherapy (RT) in combination with radiation sensitizers, (ii) dose-intensive, induction chemotherapy with hematopoietic support followed in sequence with RT applied as a "consolidation' therapy, and (iii) the interleafed application of phase-specific chemotherapeutic agents and hyperfractionated external beam radiotherapy (HFEBRT) referred to as "chemoradiotherapy'.

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Year:  1996        PMID: 8832463     DOI: 10.1007/bf00250200

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  97 in total

1.  High-dose methotrexate with citrovorum factor rescue for the treatment of central nervous system tumors in children.

Authors:  G Rosen; F Ghavimi; A Nirenberg; C Mosende; B M Mehta
Journal:  Cancer Treat Rep       Date:  1977-07

Review 2.  The hazards of therapeutic iradiation of the central nervous system.

Authors:  S Kramer
Journal:  Clin Neurosurg       Date:  1968

3.  Hyperfractionated radiation therapy in brain stem tumors. Results of treatment at the 7020 cGy dose level of Pediatric Oncology Group study #8495.

Authors:  C R Freeman; J Krischer; R A Sanford; M E Cohen; P C Burger; L Kun; E C Halperin; I Crocker; M Wharam
Journal:  Cancer       Date:  1991-08-01       Impact factor: 6.860

4.  High-dose carboplatin in combination with etoposide (JET regimen) for childhood brain tumors.

Authors:  M A Castello; A Clerico; G Deb; C Dominici; P Fidani; A Donfrancesco
Journal:  Am J Pediatr Hematol Oncol       Date:  1990

Review 5.  Preirradiation cisplatin and etoposide in the treatment of high-risk medulloblastoma and other malignant embryonal tumors of the central nervous system: a phase II study.

Authors:  E H Kovnar; S J Kellie; M E Horowitz; R A Sanford; J W Langston; R K Mulhern; J J Jenkins; E C Douglass; E E Etcubanas; D L Fairclough
Journal:  J Clin Oncol       Date:  1990-02       Impact factor: 44.544

6.  Hyperfractionated radiotherapy in brain stem tumors: results of a Pediatric Oncology Group study.

Authors:  C R Freeman; J Krischer; R A Sanford; P C Burger; M Cohen; D Norris
Journal:  Int J Radiat Oncol Biol Phys       Date:  1988-08       Impact factor: 7.038

7.  Brain stem gliomas in childhood. Rational approach and treatment.

Authors:  T Tomita; D G McLone; T P Naidich
Journal:  J Neurooncol       Date:  1984       Impact factor: 4.130

Review 8.  Chemical radiosensitizers in cancer therapy.

Authors:  M A Shenoy; B B Singh
Journal:  Cancer Invest       Date:  1992       Impact factor: 2.176

9.  High-dose cyclophosphamide chemotherapy for recurrent CNS tumors in children.

Authors:  J C Allen; L Helson
Journal:  J Neurosurg       Date:  1981-11       Impact factor: 5.115

10.  Magnetic resonance scans should replace biopsies for the diagnosis of diffuse brain stem gliomas: a report from the Children's Cancer Group.

Authors:  A L Albright; R J Packer; R Zimmerman; L B Rorke; J Boyett; G D Hammond
Journal:  Neurosurgery       Date:  1993-12       Impact factor: 4.654

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  17 in total

1.  Apparent diffusion coefficient histogram metrics correlate with survival in diffuse intrinsic pontine glioma: a report from the Pediatric Brain Tumor Consortium.

Authors:  Tina Young Poussaint; Sridhar Vajapeyam; Kelsey I Ricci; Ashok Panigrahy; Mehmet Kocak; Larry E Kun; James M Boyett; Ian F Pollack; Maryam Fouladi
Journal:  Neuro Oncol       Date:  2015-10-20       Impact factor: 12.300

2.  Tumor Response Assessment in Diffuse Intrinsic Pontine Glioma: Comparison of Semiautomated Volumetric, Semiautomated Linear, and Manual Linear Tumor Measurement Strategies.

Authors:  L A Gilligan; M D DeWire-Schottmiller; M Fouladi; P DeBlank; J L Leach
Journal:  AJNR Am J Neuroradiol       Date:  2020-04-30       Impact factor: 3.825

Review 3.  Management of diffuse pontine gliomas in children: recent developments.

Authors:  Rejin Kebudi; Fatma Betul Cakir
Journal:  Paediatr Drugs       Date:  2013-10       Impact factor: 3.022

4.  Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium.

Authors:  Katherine A Zukotynski; Frederic H Fahey; Mehmet Kocak; Abass Alavi; Terence Z Wong; S Ted Treves; Barry L Shulkin; Daphne A Haas-Kogan; Jeffrey R Geyer; Sridhar Vajapeyam; James M Boyett; Larry E Kun; Tina Young Poussaint
Journal:  J Nucl Med       Date:  2011-01-13       Impact factor: 10.057

5.  Diffuse and focal brain stem tumors in childhood: prognostic factors and surgical outcome. Experience in a single institution.

Authors:  A Sandri; N Sardi; L Genitori; F Giordano; P Peretta; M E Basso; D Bertin; L Mastrodicasa; L Todisco; F Mussa; M Forni; U Ricardi; L Cordero di Montezemolo; E Madon
Journal:  Childs Nerv Syst       Date:  2006-03-28       Impact factor: 1.475

Review 6.  The role of surgery in pediatric gliomas.

Authors:  I F Pollack
Journal:  J Neurooncol       Date:  1999-05       Impact factor: 4.130

7.  Clinically applicable human adipose tissue-derived mesenchymal stem cells delivering therapeutic genes to brainstem gliomas.

Authors:  S A Choi; Y E Lee; P A Kwak; J Y Lee; S S Kim; S J Lee; J H Phi; K-C Wang; J Song; S H Song; K M Joo; S-K Kim
Journal:  Cancer Gene Ther       Date:  2015-05-29       Impact factor: 5.987

8.  A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas.

Authors:  J Russell Geyer; Clinton F Stewart; Mehmet Kocak; Alberto Broniscer; Peter Phillips; James G Douglas; Susan M Blaney; Roger J Packer; Sri Gururangan; Anu Banerjee; Mark W Kieran; Larry E Kun; Richard J Gilbertson; James M Boyett
Journal:  Eur J Cancer       Date:  2010-08-12       Impact factor: 9.162

9.  MRI as a central component of clinical trials analysis in brainstem glioma: a report from the Pediatric Brain Tumor Consortium (PBTC).

Authors:  Tina Young Poussaint; Mehmet Kocak; Sridhar Vajapeyam; Roger I Packer; Richard L Robertson; Russell Geyer; Daphne Haas-Kogan; Ian F Pollack; Gilbert Vezina; Robert Zimmerman; Soonmee Cha; Zoltan Patay; James M Boyett; Larry E Kun
Journal:  Neuro Oncol       Date:  2011-02-04       Impact factor: 12.300

10.  Parametric Response Mapping of Apparent Diffusion Coefficient as an Imaging Biomarker to Distinguish Pseudoprogression from True Tumor Progression in Peptide-Based Vaccine Therapy for Pediatric Diffuse Intrinsic Pontine Glioma.

Authors:  R Ceschin; B F Kurland; S R Abberbock; B M Ellingson; H Okada; R I Jakacki; I F Pollack; A Panigrahy
Journal:  AJNR Am J Neuroradiol       Date:  2015-09-03       Impact factor: 3.825

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