Literature DB >> 8829534

Homobotcinolide: a biologically active natural homolog of botcinolide from Botrytis cinerea.

H G Cutler1, S R Parker, S A Ross, F G Crumley, P R Schreiner.   

Abstract

A novel natural product exhibiting biological activity was isolated from a strain of Botrytis cinerea that had infected raspberry fruit (Rubus ideaus). Liquid fermentation and bioassay-directed fractionation of the organism yielded a compound with molecular formula C22H38O8 that is trivially named homobotcinolide. It significantly inhibited etiolated wheat coleoptile growth. Greenhouse-grown bean, corn, and tobacco plants were also affected by exogenous application of homobotcinolide, severe chlorosis and necrosis being exhibited in corn. The compound is a polyhydroxylated nonalactone esterified with 4-hydroxy-2-decenoic acid.

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Year:  1996        PMID: 8829534     DOI: 10.1271/bbb.60.656

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  2 in total

1.  Botcinic acid biosynthesis in Botrytis cinerea relies on a subtelomeric gene cluster surrounded by relics of transposons and is regulated by the Zn2Cys6 transcription factor BcBoa13.

Authors:  Antoine Porquier; Javier Moraga; Guillaume Morgant; Bérengère Dalmais; Adeline Simon; Hind Sghyer; Isidro G Collado; Muriel Viaud
Journal:  Curr Genet       Date:  2019-03-08       Impact factor: 3.886

2.  Resistance to Botrytis cinerea in Solanum lycopersicoides involves widespread transcriptional reprogramming.

Authors:  Jonathon E Smith; Bemnet Mengesha; Hua Tang; Tesfaye Mengiste; Burton H Bluhm
Journal:  BMC Genomics       Date:  2014-05-03       Impact factor: 3.969

  2 in total

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