Literature DB >> 8828726

The pupillary response to tropicamide in Alzheimer's disease.

M Fridh1, U Havelius, G Elofsson, B Hindfelt.   

Abstract

An increased pupillary response to a weak solution of tropicamide has recently been suggested to be diagnostic for Alzheimer's disease. If so, it would have far-reaching implications. We performed a masked study involving 17 patients with Alzheimer's disease and 20 mentally healthy controls with respect to the pupillary response induced by tropicamide. We found no significant difference in pupillary dilatation between patients and controls (19.7 +/- 11% versus 19.1 +/- 9%; p = 0.19).

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Year:  1996        PMID: 8828726     DOI: 10.1111/j.1600-0420.1996.tb00091.x

Source DB:  PubMed          Journal:  Acta Ophthalmol Scand        ISSN: 1395-3907


  2 in total

1.  Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers.

Authors:  Shaun M Frost; Yogesan Kanagasingam; Hamid R Sohrabi; Kevin Taddei; Randall Bateman; John Morris; Tammie Benzinger; Alison Goate; Colin L Masters; Ralph N Martins
Journal:  Curr Alzheimer Res       Date:  2013-10       Impact factor: 3.498

2.  Enhancing Diagnostic Accuracy of aMCI in the Elderly: Combination of Olfactory Test, Pupillary Response Test, BDNF Plasma Level, and APOE Genotype.

Authors:  Yuda Turana; Teguh Asaat S Ranakusuma; Jan Sudir Purba; Nurmiati Amir; Siti Airiza Ahmad; Moh Hasan Machfoed; Yvonne Suzy Handayani; Sarwono Waspadji
Journal:  Int J Alzheimers Dis       Date:  2014-02-02
  2 in total

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