Literature DB >> 8828615

Effect of L-dopa on visual evoked potentials and neuropsychological tests in adult phenylketonuria patients.

K Ullrich1, J Weglage, C Oberwittler, M Pietsch, B Fünders, H von Eckardstein, J P Colombo.   

Abstract

Eight adult, untreated patients with classical phenylketonuria received L-dopa and a decarboxylase inhibitor for 2 weeks. No effect of L-dopa therapy on choice reaction time tasks, sustained attention, frontal lobal function as well as latencies of visual evoked potentials was found. The results raise the question if adult patients with phenylketonuria really suffer from functional dopamine deficiency.

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Year:  1996        PMID： 8828615     DOI： 10.1007/pl00014256

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  20 in total

1.  Inhibition of L-[18F]fluorodopa uptake into human brain by amino acids demonstrated by positron emission tomography.

Authors:  K L Leenders; W H Poewe; A J Palmer; D P Brenton; R S Frackowiak
Journal:  Ann Neurol       Date:  1986-08       Impact factor: 10.422

2.  Investigations of the functional anatomy of attention using the Stroop test.

Authors:  C J Bench; C D Frith; P M Grasby; K J Friston; E Paulesu; R S Frackowiak; R J Dolan
Journal:  Neuropsychologia       Date:  1993-09       Impact factor: 3.139

3.  Dopamine depletion slows retinal transmission.

Authors:  R S Dyer; W E Howell; R C MacPhail
Journal:  Exp Neurol       Date:  1981-02       Impact factor: 5.330

4.  Neuropsychology of early-treated phenylketonuria: specific executive function deficits.

Authors:  M C Welsh; B F Pennington; S Ozonoff; B Rouse; E R McCabe
Journal:  Child Dev       Date:  1990-12

5.  Effects of phenylalanine on the release of endogenous dopamine from rat striatal slices.

Authors:  J D Milner; K Irie; R J Wurtman
Journal:  J Neurochem       Date:  1986-11       Impact factor: 5.372

6.  Dopaminergic deficiency and delayed visual evoked potentials in humans.

Authors:  I Bodis-Wollner; M D Yahr; L Mylin; J Thornton
Journal:  Ann Neurol       Date:  1982-05       Impact factor: 10.422

7.  Effect of high-dose tyrosine supplementation on brain function in adults with phenylketonuria.

Authors:  J Pietz; R Landwehr; A Kutscha; H Schmidt; L de Sonneville; F K Trefz
Journal:  J Pediatr       Date:  1995-12       Impact factor: 4.406

8.  The effect of hyperphenylalaninaemia on the muscarinic acetylcholine receptor in the HPH-5 mouse brain.

Authors:  F A Hommes
Journal:  J Inherit Metab Dis       Date:  1993       Impact factor: 4.982

Review 9.  White matter abnormalities in phenylketonuria: results of magnetic resonance measurements.

Authors:  K Ullrich; H Möller; J Weglage; G Schuierer; U Bick; A Ludolph; H Hahn-Ullrich; B Fünders; H G Koch
Journal:  Acta Paediatr Suppl       Date:  1994-12

10.  The inhibitory action of monoamines on lateral geniculate neurones.

Authors:  J W Phillis; A K Tebècis; D H York
Journal:  J Physiol       Date:  1967-06       Impact factor: 5.182
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  5 in total

Review 1.  Large neutral amino acids in the treatment of PKU: from theory to practice.

Authors:  Francjan J van Spronsen; Martijn J de Groot; Marieke Hoeksma; Dirk-Jan Reijngoud; Margreet van Rijn
Journal:  J Inherit Metab Dis       Date:  2010-10-26       Impact factor: 4.982

2.  State regulation and response inhibition in children with ADHD and children with early- and continuously treated phenylketonuria: an event-related potential comparison.

Authors:  J R Wiersema; J J van der Meere; H Roeyers
Journal:  J Inherit Metab Dis       Date:  2005       Impact factor: 4.750

3.  Pre-attentive processing in children with early and continuously-treated PKU. Effects of concurrent Phe level and lifetime dietary control.

Authors:  Leo M J de Sonneville; Stephan C J Huijbregts; Robert Licht; Joseph A Sergeant; Francjan J van Spronsen
Journal:  J Inherit Metab Dis       Date:  2011-05-04       Impact factor: 4.982

4.  Response variability in Attention-Deficit/Hyperactivity Disorder: a neuronal and glial energetics hypothesis.

Authors:  Vivienne A Russell; Robert D Oades; Rosemary Tannock; Peter R Killeen; Judith G Auerbach; Espen B Johansen; Terje Sagvolden
Journal:  Behav Brain Funct       Date:  2006-08-23       Impact factor: 3.759

Review 5.  Systematic Review and Meta-Analysis of Neuropsychiatric Symptoms and Executive Functioning in Adults With Phenylketonuria.

Authors:  Deborah A Bilder; J Kay Noel; Erin R Baker; William Irish; Yinpu Chen; Markus J Merilainen; Suyash Prasad; Barbara J Winslow
Journal:  Dev Neuropsychol       Date:  2016-11-02       Impact factor: 2.253
  5 in total

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