Literature DB >> 882858

Brain and blood lead in acute intoxication.

H Savolainen, J Kilpiö.   

Abstract

Administering lead acetate in drinking water to adult male rats resulted in an elevated lead content in blood and brain during 11 subsequent days. The brain and blood lead contents were proportional to each other although the interdependency changed according to the cumulative dose and equilibration period. The present data indicate that the permeability of the blood-brain barrier towards inorganic lead may be dose-dependent and saturable with high doses of the metal.

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Year:  1977        PMID: 882858     DOI: 10.5271/sjweh.2788

Source DB:  PubMed          Journal:  Scand J Work Environ Health        ISSN: 0355-3140            Impact factor:   5.024


  3 in total

1.  Neuropsychological test results and symptoms among workers with well-defined long-term exposure to lead.

Authors:  C Hogstedt; M Hane; A Agrell; L Bodin
Journal:  Br J Ind Med       Date:  1983-02

2.  Biotransformational and neurophysiological changes in rabbits exposed to lead.

Authors:  E Hietanen; J Kilpiö; M Närhi; H Savolainen; H Vainio
Journal:  Arch Environ Contam Toxicol       Date:  1980       Impact factor: 2.804

3.  Comparative toxicity and tissue distribution of lead acetate in weanling and adult rats.

Authors:  J I Rader; J T Peeler; K R Mahaffey
Journal:  Environ Health Perspect       Date:  1981-12       Impact factor: 9.031

  3 in total

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