Literature DB >> 882847

Enhancing effect of levamisole on the phagocytic activity of human neutrophil polymorphonuclear leucocytes in vitro.

L Molin, O Stendahl.   

Abstract

The effect of levamisole on the phagocytic activity of normal human polymorphonuclear neutrophil leucocytes has been studied in vitro. In concentrations comparable with the serum levels obtained in treatment with levamisole perorally, the engulfment of heat-killed yeast cells is moderately but significantly increased. It is shown that levamisole can only stimulate phagocytosis of adequately opsonized particles. The action of the drug is still unknown but appears to be directly linked to the phagocytic cell.

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Year:  1977        PMID: 882847     DOI: 10.1111/j.1600-0609.1977.tb02724.x

Source DB:  PubMed          Journal:  Scand J Haematol        ISSN: 0036-553X


  3 in total

1.  The in vitro evaluation of certain neutrophil and lymphocyte functions following the ingestion of 150 mg oral dose of levamisole: assessment of the extent and duration of stimulation of neutrophil chemotaxis, protein iodination and lymphocyte transformation.

Authors:  R Anderson; R Oosthuizen; A Theron; A J Van Rensburg
Journal:  Clin Exp Immunol       Date:  1979-03       Impact factor: 4.330

2.  Cellular phagocytic studies in rheumatoid arthritis patients treated with levamisole.

Authors:  K M Wynne; P A Dieppe; J Scott; E C Huskisson
Journal:  Ann Rheum Dis       Date:  1981-08       Impact factor: 19.103

3.  Effect of rifampin, levamisole, and cytoplasmic protein antigen from Mycobacterium microti on 5'-nucleotidase production by guinea pig macrophages.

Authors:  A P Bautista
Journal:  Antimicrob Agents Chemother       Date:  1982-02       Impact factor: 5.191

  3 in total

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